Methods in Molecular Biology

Cancer Systems Biology

Methods and Protocols

Editors: von Stechow, Louise (Ed.)

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  • Includes cutting-edge methods and Protocols
  • Provides step-by-step detail essential for reproducibles results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-4939-7493-1
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Hardcover $139.00
price for USA in USD
  • ISBN 978-1-4939-7492-4
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Softcover $139.00
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  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: February 1, 2019
  • ISBN 978-1-4939-8503-6
  • Free shipping for individuals worldwide
About this book

This book comprises protocols describing systems biology methodologies and computational tools, offering a variety of ways to analyze different types of high-throughput cancer data. Chapters give an overview over data types available in large-scale data repositories and state-of-the-art methods used in the field of cancer systems biology.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Cancer Systems Biology : Methods and Protocols aims to ensure successful results in the further study of this vital field.

The chapters "Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels", "Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research" and "Phosphoproteomics-based Profiling of Kinase Activities in Cancer Cells" are available open access under a CC BY 4.0 license via link.springer.com.


Table of contents (17 chapters)

Table of contents (17 chapters)
  • Detection of Combinatorial Mutational Patterns in Human Cancer Genomes by Exclusivity Analysis

    Tan, Hua (et al.)

    Pages 3-11

  • Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data

    Kedaigle, Amanda J. (et al.)

    Pages 13-26

  • Analyzing DNA Methylation Patterns During Tumor Evolution

    Pan, Heng (et al.)

    Pages 27-53

  • MicroRNA Networks in Breast Cancer Cells

    Tahiri, Andliena (et al.)

    Pages 55-81

  • Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels

    Campbell, James (et al.)

    Pages 83-99

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7493-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA in USD
  • ISBN 978-1-4939-7492-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: February 1, 2019
  • ISBN 978-1-4939-8503-6
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Systems Biology
Book Subtitle
Methods and Protocols
Editors
  • Louise von Stechow
Series Title
Methods in Molecular Biology
Series Volume
1711
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media LLC
eBook ISBN
978-1-4939-7493-1
DOI
10.1007/978-1-4939-7493-1
Hardcover ISBN
978-1-4939-7492-4
Softcover ISBN
978-1-4939-8503-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 402
Number of Illustrations
10 b/w illustrations, 76 illustrations in colour
Topics