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Neuromethods

Genomic Mosaicism in Neurons and Other Cell Types

Editors: Frade, Jose Maria, Gage, Fred H. (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $149.00
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  • ISBN 978-1-4939-7280-7
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Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-7279-1
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  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
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  • ISBN 978-1-4939-8440-4
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About this book

This volume presents methods for the analysis of genomic variability in vertebrate neurons and broadens our knowledge in the ways we understand the brain and its neurons. The chapters in this book are divided into 5 parts, and cover the following topics: principles and approaches for discovery of somatic mosaicism in the brain, aneuploidy and ploidy variation, DNA copy number variation, LINE-1 retrotransposition, and genetic and genomic mosaicism in aging and disease. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Genomic Mosaicism in Neurons and Other Cell Types is a valuable resource for learning about the latest techniques for the analysis of genome and genetic mosaicism in vertebrate neurons.

Table of contents (17 chapters)

Table of contents (17 chapters)
  • Principles and Approaches for Discovery and Validation of Somatic Mosaicism in the Human Brain

    Pages 3-24

    Abyzov, Alexej, Ph.D. (et al.)

  • FISH-Based Assays for Detecting Genomic (Chromosomal) Mosaicism in Human Brain Cells

    Pages 27-41

    Yurov, Yuri B. (et al.)

  • Flow Cytometric and Sorting Analyses for Nuclear DNA Content, Nucleotide Sequencing, and Interphase FISH

    Pages 43-55

    Kaeser, Gwendolyn E. (et al.)

  • Flow Cytometric Quantification, Isolation, and Subsequent Epigenetic Analysis of Tetraploid Neurons

    Pages 57-80

    López-Sánchez, Noelia (et al.)

  • A Cytomic Approach Towards Genomic Individuality of Neurons

    Pages 81-106

    Arendt, Thomas (et al.)

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7280-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-7279-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-1-4939-8440-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genomic Mosaicism in Neurons and Other Cell Types
Editors
  • Jose Maria Frade
  • Fred H. Gage
Series Title
Neuromethods
Series Volume
131
Copyright
2017
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media LLC
eBook ISBN
978-1-4939-7280-7
DOI
10.1007/978-1-4939-7280-7
Hardcover ISBN
978-1-4939-7279-1
Softcover ISBN
978-1-4939-8440-4
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XVI, 382
Number of Illustrations
23 b/w illustrations, 67 illustrations in colour
Topics