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Methods in Molecular Biology

Drug Safety Evaluation

Methods and Protocols

Editors: Gautier, Jean-Charles (Ed.)

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  • Includes cutting-edge methods and protocols 
    Provides step-by-step detail essential for reproducible results
    Contains key notes and implementation advice from the experts

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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7172-5
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Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-7170-1
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  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
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  • ISBN 978-1-4939-8406-0
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  • Usually dispatched within 3 to 5 business days.
About this book

This second edition provides up-to-date chapters and new chapters focusing on the most recent advances in the field of drug safety evaluation. Divided into seven parts, chapters detail specific aspects related to the experimental design of preclinical studies conducted to support the safety of pediatric and combination drugs, necropsy and histopathology evaluation, mass spectrometry imaging, genetic toxicology protocols including the Pig-a mutation assay, safety pharmacology methods such as automatization of patch-clamp procedures, target safety assessment for investigative toxicology, screening assays for developmental toxicology, and methods to characterize novel translational safety biomarkers like microRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.

Authoritative and practical, Drug Safety Evaluation: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Table of contents (23 chapters)

Table of contents (23 chapters)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7172-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-7170-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8406-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Drug Safety Evaluation
Book Subtitle
Methods and Protocols
Editors
  • Jean-Charles Gautier
Series Title
Methods in Molecular Biology
Series Volume
1641
Copyright
2017
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media LLC
eBook ISBN
978-1-4939-7172-5
DOI
10.1007/978-1-4939-7172-5
Hardcover ISBN
978-1-4939-7170-1
Softcover ISBN
978-1-4939-8406-0
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XI, 427
Number of Illustrations
30 b/w illustrations, 28 illustrations in colour
Topics