Bioinformatics
Volume II: Structure, Function, and Applications
Editors: Keith, Jonathan M. (Ed.)
Free Preview- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
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- About this book
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This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and expert implementation advice to ensure positive results.
Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research. - Reviews
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“The book is as an excellent starting point for a wide audience including undergraduates, graduates and established researchers alike. The amount of detail presented for each methodological approach, coupled with extensive examples, facilitate not only the understanding of the topic but also the bridging between the various tasks associated with the mining of big (high throughput) biological datasets.” (Irina Ioana Mohorianu, zbMATH, Vol. 1384.92002, 2018)
- Table of contents (21 chapters)
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3D Computational Modeling of Proteins Using Sparse Paramagnetic NMR Data
Pages 3-21
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Inferring Function from Homology
Pages 23-40
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Inferring Functional Relationships from Conservation of Gene Order
Pages 41-63
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Structural and Functional Annotation of Long Noncoding RNAs
Pages 65-85
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Construction of Functional Gene Networks Using Phylogenetic Profiles
Pages 87-98
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Table of contents (21 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Bioinformatics
- Book Subtitle
- Volume II: Structure, Function, and Applications
- Editors
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- Jonathan M. Keith
- Series Title
- Methods in Molecular Biology
- Series Volume
- 1526
- Copyright
- 2017
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4939-6613-4
- DOI
- 10.1007/978-1-4939-6613-4
- Hardcover ISBN
- 978-1-4939-6611-0
- Softcover ISBN
- 978-1-4939-8250-9
- Series ISSN
- 1064-3745
- Edition Number
- 2
- Number of Pages
- XI, 426
- Number of Illustrations
- 62 b/w illustrations, 26 illustrations in colour
- Topics