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Cancer Gene Networks

  • Book
  • © 2017

Overview

Editors:
  1. Usha Kasid

    1. Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Robert Clarke

    1. Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1513)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Introduction: Cancer Gene Networks

    • Robert Clarke
    Pages 1-9

  3. Emerging Methods in Chemoproteomics with Relevance to Drug Discovery

    • Chuong Nguyen, Graham M. West, Kieran F. Geoghegan
    Pages 11-22

  4. ANXA7-GTPase as Tumor Suppressor: Mechanisms and Therapeutic Opportunities

    • Ximena Leighton, Ofer Eidelman, Catherine Jozwik, Harvey B. Pollard, Meera Srivastava
    Pages 23-35

  5. Experimental and Study Design Considerations for Uncovering Oncometabolites

    • Majda Haznadar, Ewy A. Mathé
    Pages 37-47

  6. Targeting Deubiquitinating Enzymes and Autophagy in Cancer

    • Ashley Mooneyham, Martina Bazzaro
    Pages 49-59

  7. Quantitative Clinical Imaging Methods for Monitoring Intratumoral Evolution

    • Joo Yeun Kim, Robert A. Gatenby
    Pages 61-81

  8. Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression

    • Timothy F. Day, Rajshree R. Mewani, Joshua Starr, Xin Li, Debyani Chakravarty, Habtom Ressom et al.
    Pages 83-100

  9. Network-Oriented Approaches to Anticancer Drug Response

    • Paola Lecca, Angela Re
    Pages 101-117

  10. CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells

    • Nipun Verma, Zengrong Zhu, Danwei Huangfu
    Pages 119-140

  11. Complete Transcriptome RNA-Seq

    • David F. B. Miller, Pearlly Yan, Fang Fang, Aaron Buechlein, Karl Kroll, David Frankhouser et al.
    Pages 141-162

  12. Computational Methods and Correlation of Exon-skipping Events with Splicing, Transcription, and Epigenetic Factors

    • Jianbo Wang, Zhenqing Ye, Tim H. Huang, Huidong Shi, Victor X. Jin
    Pages 163-170

  13. Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma

    • Wenting Zhang, Woo Y. Lee, Jenny Zilberberg
    Pages 171-191

  14. microRNA Target Prediction

    • William Ritchie
    Pages 193-200

  15. Evaluating the Delivery of Proteins to the Cytosol of Mammalian Cells

    • Andrea L. J. Marschall, Congcong Zhang, Stefan Dübel
    Pages 201-208

  16. Validation of Biomarker Proteins Using Reverse Capture Protein Microarrays

    • Catherine Jozwik, Ofer Eidelman, Joshua Starr, Harvey B. Pollard, Meera Srivastava
    Pages 209-222

  17. Chemical Synthesis of Activity-Based Diubiquitin Probes

    • Guorui Li, Libo Yuan, Zhihao Zhuang
    Pages 223-232

  18. Profiling the Dual Enzymatic Activities of the Serine/Threonine Kinase IRE1α

    • Hannah C. Feldman, Dustin J. Maly
    Pages 233-242

  19. Back Matter

    Pages 243-248
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Keywords

About this book

This volume is a valuable and timely resource for a broad audience with interests in basic and translational cancer biology, cancer drug development, as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, Cancer Gene Networks aims to ensure successful results in the further study of this evolving and vital field. Ultimately these efforts will guide development of transformative strategies for cancer diagnosis and treatment.

Editors and Affiliations

  • Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, USA

    Usha Kasid, Robert Clarke

Bibliographic Information

  • Book Title: Cancer Gene Networks

  • Editors: Usha Kasid, Robert Clarke

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-6539-7

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-1-4939-6537-3Published: 03 November 2016

  • Softcover ISBN: 978-1-4939-8230-1Published: 27 June 2018

  • eBook ISBN: 978-1-4939-6539-7Published: 02 November 2016

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 248

  • Number of Illustrations: 19 b/w illustrations, 41 illustrations in colour

  • Topics: Cancer Research

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