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Methods in Molecular Biology

ERK Signaling

Methods and Protocols

Editors: Jimenez, Gerardo (Ed.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains keynotes and implementation advice from the experts
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-6424-6
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Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-6422-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-8195-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides a collection of techniques and approaches for the study of ERK signaling. It begins with a historical perspective of genetic and molecular discoveries, followed by chapters covering specific topics in a broad range of experimental systems, including in vitro assays of EGFR and ERK activities; proteomic and genome-wide analyses of ERK signaling targets; cell biological, genetic, quantitative and imaging approaches in cells and model organisms; and integrated mathematical modeling of the ERK pathway. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, ERK Signaling: Methods and Protocols will aid and stimulate further advances in the vibrant field of ERK signaling.

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Table of contents (29 chapters)

Table of contents (29 chapters)
  • How Genetics Has Helped Piece Together the MAPK Signaling Pathway

    Pages 1-21

    Ashton-Beaucage, Dariel (et al.)

  • In Vitro Enzyme Kinetics Analysis of EGFR

    Pages 23-33

    Wang, Zhihong (et al.)

  • High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast Cells

    Pages 35-52

    Yoshimoto, Nobuo (et al.)

  • Structural Studies of ERK2 Protein Complexes

    Pages 53-63

    Weijman, Johannes F. (et al.)

  • Isolation and Characterization of Intrinsically Active (MEK-Independent) Mutants of Mpk1/Erk

    Pages 65-88

    Goshen-Lago, Tal (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-6424-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-6422-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-8195-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
ERK Signaling
Book Subtitle
Methods and Protocols
Editors
  • Gerardo Jimenez
Series Title
Methods in Molecular Biology
Series Volume
1487
Copyright
2017
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-6424-6
DOI
10.1007/978-1-4939-6424-6
Hardcover ISBN
978-1-4939-6422-2
Softcover ISBN
978-1-4939-8195-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 440
Number of Illustrations
19 b/w illustrations, 21 illustrations in colour
Topics