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Molecular and Cellular Mechanobiology

  • Book
  • © 2016

Overview

  • Helps physiologists and biologists interested in mechanobiology but new to the field to understand the impact of mechanobiology on physiological regulation in health and disease
  • Details the roles of mechanobiology in the pathogenesis, diagnosis, treatment and prevention of disease
  • Covers basic principles in physiological conditions, as well as examples of clinical applications
  • Includes supplementary material: sn.pub/extras

Part of the book series: Physiology in Health and Disease (PIHD)

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Table of contents (13 chapters)

  1. Mechanosensors

  2. Transducers

  3. Epigenetic and Genetic Regulations in the Nucleus

  4. Applications

Keywords

About this book

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Editors and Affiliations

  • Professor of Bioengineering and Medicine, University of California, San Diego, La Jolla, USA

    Shu Chien

  • Associate Professor of Bioengineering, University of California, San Diego, La Jolla, USA

    Adam J. Engler, Peter Yingxiao Wang

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