Physiology in Health and Disease

Molecular and Cellular Mechanobiology

Editors: Chien, Shu, Engler, Adam J., Wang, Peter Yingxiao (Eds.)

  • Helps physiologists and biologists interested in mechanobiology but new to the field to understand the impact of mechanobiology on physiological regulation in health and disease
  • Details the roles of mechanobiology in the pathogenesis, diagnosis, treatment and prevention of diseaseCovers basic principles in physiological conditions, as well as examples of clinical applications
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eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-4939-5617-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA in USD
  • ISBN 978-1-4939-5615-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Table of contents (13 chapters)

  • The Primary Cilium as a Strain Amplifying Microdomain for Mechanotransduction at the Cell Membrane

    Moore, Emily R. (et al.)

    Pages 3-27

  • Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress

    Chen, Li-Jing (et al.)

    Pages 29-56

  • Cadherins in Mechanotransduction

    Leckband, D. E.

    Pages 57-80

  • Emerging Roles of YAP/TAZ in Mechanobiology

    Sun, Yubing (et al.)

    Pages 83-96

  • Role of Rho GTPases in Mechanobiology

    McCulloch, Christopher A.

    Pages 97-117

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-4939-5617-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA in USD
  • ISBN 978-1-4939-5615-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular and Cellular Mechanobiology
Editors
  • Shu Chien
  • Adam J. Engler
  • Peter Yingxiao Wang
Series Title
Physiology in Health and Disease
Copyright
2016
Publisher
Springer-Verlag New York
Copyright Holder
The American Physiological Society
eBook ISBN
978-1-4939-5617-3
DOI
10.1007/978-1-4939-5617-3
Hardcover ISBN
978-1-4939-5615-9
Edition Number
1
Number of Pages
XIII, 302
Number of Illustrations and Tables
1 b/w illustrations, 57 illustrations in colour
Topics