Methods in Pharmacology and Toxicology

G Protein-Coupled Receptor Kinases

Editors: Gurevich, Vsevolod V., Gurevich, Eugenia V., Tesmer, John J.G. (Eds.)

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  • Features detailed examinations of known GRK-dependent mechanisms, both associated with GPCR functions and receptor-independent
  • Covers a wide range of studies from invertebrates to humans
  • Provides practical advice from the experts on how to continue research on GRKs
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-3798-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-3796-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-8142-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the receptor-independent. The chapters cover a wide range of studies from invertebrates to humans, with sections of the volume covering GRK structure, mechanisms of activation, and interaction with GPCRs, GRKs in cell signaling, as well as physiological and pathophysiological mechanisms regulated by GRKs.  Written for the Methods in Pharmacology and Toxicology series, this book features the kind of practical detail necessary for success in the laboratory. Authoritative and timely, G Protein-Coupled Receptor Kinases features the kind of comprehensive mechanistic elucidation of GRK functions and their regulation in cells necessary for a better understanding of cell biology as well as for devising novel research approaches and therapeutic strategies.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • G Protein-Coupled Receptor Kinases (GRKs) History: Evolution and Discovery

    Pages 3-22

    Gurevich, Vsevolod V. (et al.)

  • Structure and Function of G-Protein-Coupled Receptor Kinases 1 and 7

    Pages 25-43

    Orban, Tivadar (et al.)

  • Visual G Protein-Coupled Receptor Kinases

    Pages 45-57

    Hsu, Chih-Chun (et al.)

  • Molecular Basis for Targeting, Inhibition, and Receptor Phosphorylation in the G Protein-Coupled Receptor Kinase 4 Subfamily

    Pages 59-74

    Beyett, Tyler S. (et al.)

  • “Barcode” and Differential Effects of GPCR Phosphorylation by Different GRKs

    Pages 75-120

    Xiao, Kunhong, M.D., Ph.D. (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-3798-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-3796-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-8142-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
G Protein-Coupled Receptor Kinases
Editors
  • Vsevolod V. Gurevich
  • Eugenia V. Gurevich
  • John J.G. Tesmer
Series Title
Methods in Pharmacology and Toxicology
Copyright
2016
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-3798-1
DOI
10.1007/978-1-4939-3798-1
Hardcover ISBN
978-1-4939-3796-7
Softcover ISBN
978-1-4939-8142-7
Series ISSN
1557-2153
Edition Number
1
Number of Pages
XI, 329
Number of Illustrations
3 b/w illustrations, 33 illustrations in colour
Topics