Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1382)
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Table of contents (32 protocols)
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Front Matter
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Introduction
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Front Matter
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Viral Vector Production
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Front Matter
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Viral Vector Tropism
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Front Matter
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Delivery Methods
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Front Matter
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Keywords
About this book
This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Gene Therapy for Neurological Disorders
Book Subtitle: Methods and Protocols
Editors: Fredric P. Manfredsson
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-3271-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2016
Hardcover ISBN: 978-1-4939-3270-2Published: 26 November 2015
Softcover ISBN: 978-1-4939-4896-3Published: 23 August 2016
eBook ISBN: 978-1-4939-3271-9Published: 26 November 2015
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 493
Topics: Neurosciences, Human Genetics, Neurology