Stem Cell Biology and Regenerative Medicine

Regenerative Medicine for Degenerative Muscle Diseases

Editors: Childers, Martin K. (Ed.)

Free Preview
  • Examines new and developing regenerative medicine enabling technologies for the treatment of patients with degenerative diseases of skeletal muscle
  • Provides a rapid look at new approaches to old conditions that impact thousands of patients and their families worldwide
  • Presents a new regenerative medicine approach to treatment or discovery
see more benefits

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-3228-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-3227-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8001-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an array of contexts and biological systems. The topics covered include: How are urine cells from a patient with Duchenne muscular dystrophy transformed into beating heart cells? What can reprogrammed cells tell us about heart muscle failure? What do gene mutations mean for those born with a muscle disease? How are manufacturing methods applied to human stem cells? Does therapeutic exercise benefit those patients who receive engineered limb muscle? Is there practical advice about nutrition to enhance muscle function for the Duchenne patient? Can microRNAs be useful to regenerate diseased muscle?

 Regenerative Medicine for Degenerative Muscle Diseases is ideal for scientists and clinicians from varying disciplines in genetics, cell biology, virology, cell-based manufacturing, rehabilitation medicine, nutrition, veterinary medicine and neurosurgery. The reader will see how transformative changes occur in medicine that can powerfully impact the future for patients suffering from inherited disorders affecting muscles of the body, including the heart.

About the authors

Martin K. (Casey) Childers, D.O., Ph.D.  is a professor in the Department of Rehabilitation Medicine and Investigator at the Institute for Stem Cell & Regenerative Medicine, University of Washington. He is a graduate of Seattle Pacific University  (B.A., Music Performance), Western University (D.O., Medicine, Osteopathic) and The University of Missouri (Ph.D., Physiology & Pharmacology; residency, Rehabilitation Medicine). The Childers' laboratory works in two areas of investigation. In a series of preclinical studies, they address the hurdles required for systemic gene replacement delivery for patients with X-Linked Myotubular Myopathy (XLMTM). In other studies, they use a "disease in a dish" approach with induced pluripotent stem (iPS) cells to study heart disease in patients with Duchenne muscular dystrophy (DMD). Dr. Childers clinical medicine practice at the University of Washington Medical Center is dedicated to serve patients with neuromuscular diseases.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Regenerative Medicine Approaches to Degenerative Muscle Diseases

    Childers, Martin K. (et al.)

    Pages 1-20

  • An Overview of rAAV Vector Product Development for Gene Therapy

    Snyder, Richard O., Ph.D.

    Pages 21-37

  • Gene Discovery in Congenital Myopathy

    Smith, Laura L. (et al.)

    Pages 39-83

  • Stem Cell Transplantation for Degenerative Muscle Diseases

    Akpinar, Berkcan (et al.)

    Pages 85-108

  • Spinal Cord Cellular Therapeutics Delivery: Device Design Considerations

    Medani, Khalid, M.D. (et al.)

    Pages 109-127

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-3228-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-3227-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8001-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Regenerative Medicine for Degenerative Muscle Diseases
Editors
  • Martin K. Childers
Series Title
Stem Cell Biology and Regenerative Medicine
Copyright
2016
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-3228-3
DOI
10.1007/978-1-4939-3228-3
Hardcover ISBN
978-1-4939-3227-6
Softcover ISBN
978-1-4939-8001-7
Series ISSN
2196-8985
Edition Number
1
Number of Pages
XIII, 336
Number of Illustrations
3 b/w illustrations, 23 illustrations in colour
Topics