Happy Holidays—Our $30 Gift Card just for you, and books ship free! Shop now>>

Neuromethods

Epigenetic Methods in Neuroscience Research

Editors: Karpova, Nina N. (Ed.)

Free Preview
  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook $89.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2754-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-2753-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA in USD
  • ISBN 978-1-4939-4941-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system. Epigenetic Methods in Neuroscience Research  guides readers through methods for the analyses of chromatin remodeling, transposable elements, non-coding RNAs, such as miRNAs, and circadian oscillations, including: analysis of DNA methylation in neuronal and glial cells or small tissue samples; sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry; affinity-based detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation; chromatin immunoprecipitation, or ChIP; miRNA high-throughput profiling and the in situ detection of miRNA subtle expression in the brain; analysis of genes with alternative 3’UTRs; and the cite-specific delivery of chromatin-modifying drugs. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Concise and easy-to-use, Epigenetic Methods in Neuroscience Research provides multidisciplinary epigenetic approach to study genome, and neural, plasticity that will help the reader to successfully address the challenges associated with neurodevelopmental, psychiatric, and neurodegenerative disorders.

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Epigenetics: From Basic Biology to Chromatin-Modifying Drugs and New Potential Clinical Applications

    Pages 3-18

    Matrisciano, Francesco, M.D., Ph.D. (et al.)

  • Analysis of Brain Epigenome: A Guide to Epigenetic Methods

    Pages 19-51

    Karpova, Nina N.

  • Analysis of DNA Methylation by Bisulfite Reaction in Neural Cells as an Example of Orexin Neurons

    Pages 55-63

    Hayakawa, Koji (et al.)

  • A Protocol for the Simultaneous Analysis of Gene DNA Methylation and mRNA Expression Levels in the Rodent Brain

    Pages 65-85

    Umemori, Juzoh (et al.)

  • Simultaneous Quantification of Global 5mC and 5hmC Levels in the Nervous System Using an HPLC/MS Method

    Pages 87-96

    Ross, Daniel L. (et al.)

Buy this book

eBook $89.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2754-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-2753-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA in USD
  • ISBN 978-1-4939-4941-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Epigenetic Methods in Neuroscience Research
Editors
  • Nina N. Karpova
Series Title
Neuromethods
Series Volume
105
Copyright
2016
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2754-8
DOI
10.1007/978-1-4939-2754-8
Hardcover ISBN
978-1-4939-2753-1
Softcover ISBN
978-1-4939-4941-0
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XII, 258
Number of Illustrations
6 b/w illustrations, 37 illustrations in colour
Topics