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Animal Models of Neurodevelopmental Disorders

  • Book
  • © 2015

Overview

Editors:
  1. Jerome Y. Yager

    1. Div. Pediatric Neurology, University of Alberta Dept. Pediatrics, Edmonton, Canada

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  • Consolidates a diverse selection of animal models
  • Provides practical details from leading researchers in the field
  • Includes cutting-edge, lab-ready methodologies

Part of the book series: Neuromethods (NM, volume 104)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Unilateral Common Carotid Artery Ligation as a Model of Perinatal Asphyxia: The Original Rice–Vannucci Model

    • Antoinette Nguyen, Edward A. Armstrong, Jerome Y. Yager
    Pages 1-13

  3. Bilateral Uterine Artery Ligation (BUAL): Placental Insufficiency Causing Fetal Growth Restriction and Cerebral Palsy

    • Jennifer Corrigan, Edward A. Armstrong, Stuart Faulkner, Crystal A. Ruff, Michael Fehlings, Jerome Y. Yager
    Pages 15-28

  4. Perinatal Intracerebral Hemorrhage Model and Developmental Disability

    • Janani Kassiri, Marc Del Bigio
    Pages 29-44

  5. Preterm Rabbit Model of Glycerol-Induced Intraventricular Hemorrhage

    • Praveen Ballabh
    Pages 45-54

  6. Models of Perinatal Brain Injury in Premature and Term Newborns Resulting from Gestational Inflammation Due to Inactivated Group B Streptococcus (GBS), or Lipopolysaccharide (LPS) from E. coli and/or Immediately Postnatal Hypoxia-Ischemia (HI)

    • Julie Bergeron, Marie-Julie Allard, Clémence Guiraut, Mathilde Chevin, Alexandre Savard, Djordje Grbic et al.
    Pages 55-64

  7. Fetal Brain Activity in the Sheep Model with Intrauterine Hypoxia

    • Bryan S. Richardson, Brad Matushewski
    Pages 65-83

  8. Studies of Perinatal Asphyxial Brain Injury in the Fetal Sheep

    • Paul P. Drury, Laura Bennet, Lindsea C. Booth, Joanne O. Davidson, Guido Wassink, Alistair Jan Gunn
    Pages 85-105

  9. The Sheep as a Model of Brain Injury in the Premature Infant

    • Stephen A. Back, Art Riddle, A. Roger Hohimer
    Pages 107-128

  10. The Rabbit as a Model of Cerebral Palsy

    • Kehuan Luo, Jessica Baker, Matthew Derrick, Sidhartha Tan
    Pages 129-141

  11. A Newborn Piglet Survival Model of Post-hemorrhagic Ventricular Dilatation (PHVD)

    • Kristian Aquilina, Marianne Thoresen
    Pages 143-157

  12. Physiologic Aspects of the Piglet as a Model of Neonatal Hypoxia and Reoxygenation

    • Richdeep S. Gill, David L. Bigam, Po-Yin Cheung
    Pages 159-170

  13. The Newborn Pig Global Hypoxic-Ischemic Model of Perinatal Brain and Organ Injury

    • Elavazhagan Chakkarapani, Marianne Thoresen
    Pages 171-189

  14. Animal Models of Fetal Alcohol Spectrum Disorder

    • Wendy Comeau, Tamara Bodnar, Kristina Uban, Vivian Lam, Katarzyna Stepien, Joanne Weinberg
    Pages 191-214

  15. Modeling Intellectual Disability in Drosophila

    • Alaura Androschuk, Francois V. Bolduc
    Pages 215-237

  16. Animal Models of Cerebral Dysgenesis: Excitotoxic Brain Injury

    • Luigi Titomanlio, Leslie Schwendimann, Pierre Gressens
    Pages 239-246

  17. The Effect of Age on Brain Plasticity in Animal Models of Developmental Disability

    • Bryan Kolb, Deborah Saucier
    Pages 247-263

  18. Back Matter

    Pages 265-267
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Keywords

About this book

Providing a spectrum of models that is reflective of the various species that can be utilized in experimentation on disorders across a broad range of developmental disabilities, this volume collects expert contributions involved in investigation of the causes, outcomes, treatment, and prevention. Animal Models of Neurodevelopmental Disorders explores models of perinatal hypoxia-ischemia/cerebral palsy and stroke, autism spectrum disorder, fetal alcohol syndrome, as well as mental retardation. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Practical and authoritative, Animal Models of Neurodevelopmental Disorders serves to introduce and entice those interested in better understanding and treating these disorders to the vital animal model world of investigation.

Editors and Affiliations

  • Div. Pediatric Neurology, University of Alberta Dept. Pediatrics, Edmonton, Canada

    Jerome Y. Yager

Bibliographic Information

  • Book Title: Animal Models of Neurodevelopmental Disorders

  • Editors: Jerome Y. Yager

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-2709-8

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-2708-1Published: 20 September 2015

  • Softcover ISBN: 978-1-4939-4065-3Published: 22 October 2016

  • eBook ISBN: 978-1-4939-2709-8Published: 19 September 2015

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIII, 267

  • Number of Illustrations: 21 b/w illustrations, 43 illustrations in colour

  • Topics: Neurosciences, Human Genetics

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