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Methods in Pharmacology and Toxicology

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development

Editors: Potts, Steven J., Eberhard, David A., Wharton, Jr., Keith A. (Eds.)

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  • Explores pathology in oncologic disease and beyond, into other disease areas that have not received as much attention
  • Provides practical wisdom and examples from histopathology experts to apply to drug development programs
  • Features techniques, case studies, reviews, and collections of the authors' experiences in the field
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eBook $109.00
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  • ISBN 978-1-4939-2681-7
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Hardcover $179.99
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Softcover $139.00
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  • ISBN 978-1-4939-5420-9
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About this book

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepatitis, arthritis, celiac disease, myeloproliferative disorders, neurology, and wound healing. The authors write from years of experience in diagnostic practice and pharmaceutical drug development, aiming to educate pharmaceutical and academic scientists how to best use tissue to diagnose disease and improve the process of drug development.  As part of the Methods in Pharmacology and Toxicology series, this volume is designed to provide wisdom and examples that others can follow and apply as part of drug development.

Comprehensive and practical, Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development will inform and enlighten both tissue-focused and non-tissue-focused drug development professionals about better use and interpretation of the multidimensional data contained in a tissue biopsy.

Table of contents (24 chapters)

Table of contents (24 chapters)
  • Histopathology: A Canvas and Landscape of Disease in Drug and Diagnostic Development

    Pages 1-26

    Wharton, Keith A., Jr., M.D. Ph.D.

  • A Field Guide to Homo morphologicus for Biomedical Scientists, Or How to Convey an Understanding of Pathology to Scientists in a Biopharma Enterprise

    Pages 27-41

    Gardner, Humphrey

  • Outsourcing Tissue Histopathology Investigations in Support of Clinical Trials for Novel Therapeutics: Considerations and Perspectives

    Pages 43-63

    Wharton, Keith A., Jr. (et al.)

  • Histopathology in Mouse Models of Rheumatoid Arthritis

    Pages 65-78

    Caplazi, Patrick (et al.)

  • Markers Used for Visualization and Quantification of Blood and Lymphatic Vessels

    Pages 79-85

    Salama, Mohamed E. (et al.)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-4939-2681-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-2680-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-5420-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development
Editors
  • Steven J. Potts
  • David A. Eberhard
  • Keith A. Wharton, Jr.
Series Title
Methods in Pharmacology and Toxicology
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2681-7
DOI
10.1007/978-1-4939-2681-7
Hardcover ISBN
978-1-4939-2680-0
Softcover ISBN
978-1-4939-5420-9
Series ISSN
1557-2153
Edition Number
1
Number of Pages
XVIII, 375
Number of Illustrations
20 b/w illustrations, 37 illustrations in colour
Topics

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