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Methods in Pharmacology and Toxicology

Label-Free Biosensor Methods in Drug Discovery

Editors: Fang, Ye (Ed.)

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  • Assists academic and industrial researchers involved in drug and probe discovery to adopt label-free techniques
  • Provides fundamental and practical methods from expert researchers
  • Includes tips and key implementation advice to aid in translating techniques to your own lab
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2617-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-2616-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-4961-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the Methods in Pharmacology and Toxicology series, chapters aim to provide key detail and implementation advice to aid with progress in the lab.

Practical and thorough, Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Label-Free Technologies: Which Technique to Use and What to Watch Out for!

    Pages 3-15

    Halai, Reena (et al.)

  • Label-Free Cell Phenotypic Profiling and Screening: Techniques, Experimental Design, and Data Assessment

    Pages 17-33

    Fang, Ye

  • Surface Plasmon Resonance for Therapeutic Antibody Characterization

    Pages 35-76

    Davidoff, S. Nicole (et al.)

  • Label-Free Cell-Based Biosensor Methods in Drug Toxicology Analysis

    Pages 77-108

    Zhou, Jie (et al.)

  • Kinetics Characterization of Ligand–Receptor Interactions Using Oblique-Incidence Reflectivity Difference Method

    Pages 111-118

    Liu, Shuang (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2617-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-2616-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-4961-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Label-Free Biosensor Methods in Drug Discovery
Editors
  • Ye Fang
Series Title
Methods in Pharmacology and Toxicology
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2617-6
DOI
10.1007/978-1-4939-2617-6
Hardcover ISBN
978-1-4939-2616-9
Softcover ISBN
978-1-4939-4961-8
Series ISSN
1557-2153
Edition Number
1
Number of Pages
XI, 390
Number of Illustrations
21 b/w illustrations, 93 illustrations in colour
Topics