Editors:
- Includes cutting-edge techniques to explore gene therapy for neurological disorders
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Neuromethods (NM, volume 98)
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Table of contents (14 protocols)
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Front Matter
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Back Matter
About this book
This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in the authors’ laboratories. Although safe gene manipulation in neural cells can be achieved, it may still be years away from efficacious gene-based treatment of neurological disorders such as Parkinson's and Alzheimer’s diseases due to the complexity of the underlying genetic/molecular mechanisms and the difficulty of developing reliable animal models. Gene Delivery and Therapy for Neurological Disorders seeks to aid researchers in this vital work. Written in the popular Neuromethods series format, chapters include the kind of detailed description and expert implementation advice that leads to success in the lab.
Meticulous and authoritative, Gene Delivery and Therapy for Neurological Disorders serves as an ideal guide for researchers attempting to explore the potentials of gene therapy for neurological disorders.
Editors and Affiliations
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Queen Mary University of London, London, United Kingdom
Xuenong Bo
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Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
Joost Verhaagen
Bibliographic Information
Book Title: Gene Delivery and Therapy for Neurological Disorders
Editors: Xuenong Bo, Joost Verhaagen
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-4939-2306-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2015
Hardcover ISBN: 978-1-4939-2305-2Published: 04 February 2015
Softcover ISBN: 978-1-4939-5316-5Published: 05 October 2016
eBook ISBN: 978-1-4939-2306-9Published: 03 February 2015
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XIV, 359
Number of Illustrations: 14 b/w illustrations, 51 illustrations in colour
Topics: Neurosciences, Human Genetics, Neurology