Neuromethods

Gene Delivery and Therapy for Neurological Disorders

Editors: Bo, Xuenong, Verhaagen, Joost (Eds.)

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  • Includes cutting-edge techniques to explore gene therapy for neurological disorders
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2306-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-2305-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-5316-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in the authors’ laboratories. Although safe gene manipulation in neural cells can be achieved, it may still be years away from efficacious gene-based treatment of neurological disorders such as Parkinson's and Alzheimer’s diseases due to the complexity of the underlying genetic/molecular mechanisms and the difficulty of developing reliable animal models. Gene Delivery and Therapy for Neurological Disorders seeks to aid researchers in this vital work.  Written in the popular Neuromethods series format, chapters include the kind of detailed description and expert implementation advice that leads to success in the lab.

Meticulous and authoritative, Gene Delivery and Therapy for Neurological Disorders serves as an ideal guide for researchers attempting to explore the potentials of gene therapy for neurological disorders.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Adeno-Associated Vectors for Gene Delivery to the Nervous System

    Pages 1-22

    Mulcahy, Pádraig J. (et al.)

  • Lentiviral Vectors for Gene Delivery to the Nervous System

    Pages 23-66

    Eleftheriadou, Ioanna (et al.)

  • Gene Therapy for Parkinson’s Disease: AAV5-Mediated Delivery of Glial Cell Line-Derived Neurotrophic Factor (GDNF)

    Pages 67-83

    Blits, Bas, Ph.D. (et al.)

  • Gene Delivery and Gene Therapy for Alzheimer’s Disease

    Pages 85-120

    Woodbury, Maya (et al.)

  • Gene Therapy for Huntington’s Disease

    Pages 121-151

    Wu, Angela (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-2306-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-2305-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-5316-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Gene Delivery and Therapy for Neurological Disorders
Editors
  • Xuenong Bo
  • Joost Verhaagen
Series Title
Neuromethods
Series Volume
98
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2306-9
DOI
10.1007/978-1-4939-2306-9
Hardcover ISBN
978-1-4939-2305-2
Softcover ISBN
978-1-4939-5316-5
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XIV, 359
Number of Illustrations
14 b/w illustrations, 51 illustrations in colour
Topics