Methods in Molecular Biology

Mouse Models of Cancer

Methods and Protocols

Editors: Eferl, Robert, Casanova, Emilio (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA in USD
  • ISBN 978-1-4939-2297-0
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  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase Institutional customers should get in touch with their account manager
Hardcover $179.99
price for USA in USD
Softcover $139.00
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About this book

This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice for research on cancer and other human disorders. The chapters of this book will support scientists in choosing the most suitable mouse models for their research questions. The book provides detailed methodological information for genetic or chemical induction of different types of cancer, histomorphometric cancer analysis, and in vivo imaging, as well as protocols to investigate oncogene addiction, immune surveillance, and hallmarks of cancer such as angiogenesis or metastasis. Four review-like articles provide background information on mouse technologies and histopathologic differences between mouse and human cancers. The mouse models described in individual chapters will fuel the understanding of cancer initiation, immune system roles, tumor angiogenesis, invasion, metastasis, and the relevance of molecular diversity observed among human cancers.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and resourceful, Mouse Models of Cancers: Methods and Protocols, is a valuable laboratory resource for all researchers, from the graduate level upwards, who study cancer and new possibilities for its treatment.

Table of contents (22 chapters)

Table of contents (22 chapters)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-4939-2297-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase Institutional customers should get in touch with their account manager
Hardcover $179.99
price for USA in USD
Softcover $139.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Mouse Models of Cancer
Book Subtitle
Methods and Protocols
Editors
  • Robert Eferl
  • Emilio Casanova
Series Title
Methods in Molecular Biology
Series Volume
1267
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2297-0
DOI
10.1007/978-1-4939-2297-0
Hardcover ISBN
978-1-4939-2296-3
Softcover ISBN
978-1-4939-4844-4
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 463
Number of Illustrations
9 b/w illustrations, 87 illustrations in colour
Topics