Mitochondrial Medicine
Volume II, Manipulating Mitochondrial Function
Editors: Weissig, Volkmar, Edeas, Marvin (Eds.)
Free Preview- Includes cutting-edge methods and protocols for the manipulation of mitochondrial function
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Buy this book
- About this book
-
This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. It dedicates itself to showcasing the tremendous efforts and the progress that has been made over the last decades in developing techniques and protocols for probing, imaging, and manipulating mitochondrial functions. Mitochondrial Medicine: Volume II, Manipulating Mitochondrial Function describes techniques developed for manipulating and assessing mitochondrial function under general pathological conditions and specific disease states. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and practical, Mitochondrial Medicine provides an essential source of know-how and inspiration to all researchers who are fascinated by this tiny organelle that seems so clearly to control the life and death of a single cell and whole organisms alike.
- Table of contents (33 chapters)
-
-
DQAsomes as the Prototype of Mitochondria-Targeted Pharmaceutical Nanocarriers: Preparation, Characterization, and Use
Pages 1-11
-
Predicting Mitochondrial Targeting by Small Molecule Xenobiotics Within Living Cells Using QSAR Models
Pages 13-23
-
Targeting Mitochondria with Small Molecules: The Preparation of MitoB and MitoP as Exomarkers of Mitochondrial Hydrogen Peroxide
Pages 25-50
-
Synthesis of Triphenylphosphonium Phospholipid Conjugates for the Preparation of Mitochondriotropic Liposomes
Pages 51-57
-
Synthesis and Evaluation of 18F-Labeled Fluoroalkyl Triphenylphosphonium Salts as Mitochondrial Voltage Sensors in PET Myocardial Imaging
Pages 59-72
-
Table of contents (33 chapters)
Recommended for you
Bibliographic Information
- Bibliographic Information
-
- Book Title
- Mitochondrial Medicine
- Book Subtitle
- Volume II, Manipulating Mitochondrial Function
- Editors
-
- Volkmar Weissig
- Marvin Edeas
- Series Title
- Methods in Molecular Biology
- Series Volume
- 1265
- Copyright
- 2015
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4939-2288-8
- DOI
- 10.1007/978-1-4939-2288-8
- Hardcover ISBN
- 978-1-4939-2287-1
- Softcover ISBN
- 978-1-4939-5605-0
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- XXIII, 447
- Number of Illustrations
- 59 b/w illustrations, 65 illustrations in colour
- Topics
