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The Maze Book

Theories, Practice, and Protocols for Testing Rodent Cognition

  • Book
  • © 2015

Overview

Editors:
  1. Heather A. Bimonte-Nelson

    1. Arizona State University, Tempe, USA

    View editor publications

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  • Provides a laboratory roadmap for testing cognition in rodents with a focus on a wide variety of mazes
  • Includes step-by-step protocols for specific maze types, essential for reproducible results
  • Contains key background and theory to accompany the practical techniques
  • Includes supplementary material: sn.pub/extras

Part of the book series: Neuromethods (NM, volume 94)

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Table of contents (20 protocols)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  2. Why? Foundations of Rodent Learning and Memory: Milestones, Mazes, and Mechanisms

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Rodent Mazes and Memory: Continuing the Search for the Engram

      • Heather A. Bimonte-Nelson
      Pages 3-36

    3. The Mazes

      • Heather A. Bimonte-Nelson, Jill M. Daniel, Stephanie V. Koebele
      Pages 37-72

    4. The Watermaze

      • Richard G. M. Morris
      Pages 73-92

    5. Behavioral Consequences of Early Disruption and Injury to the Developing Brain: Studying Rodent Models

      • Dongnhu T. Truong, R. Holly Fitch
      Pages 93-120

    6. Insights into Age-Related Cognitive Decline: Coupling Neurophysiological and Behavioral Approaches

      • Lesley A. Schimanski, Carol A. Barnes
      Pages 121-142

    7. Organization and Structure of Brain Systems Supporting Memory

      • Jena B. Hales, Robert E. Clark
      Pages 143-164

    8. Pharmacologically Manipulating Learning and Memory

      • Ashley M. Fortress, Karyn M. Frick
      Pages 165-210

    9. Stress and Spatial Maze Performance in the Rat

      • Sara B. Taylor, Cheryl D. Conrad, M. Foster Olive
      Pages 211-258

    10. Genetically Modified Rodent Models: A New Generation of Translational Cognitive Science

      • Salvatore Oddo, Masashi Kitazawa
      Pages 259-283

    11. Epigenetics of Cognition and Neurodegenerative Disorders

      • Paul Coleman, Matthew Huentelman, Travis Dunckley
      Pages 285-298

    12. The Importance of Incorporating Both Sexes and Embracing Hormonal Diversity When Conducting Rodent Behavioral Assays

      • Sarah E. Mennenga, Heather A. Bimonte-Nelson
      Pages 299-321

    13. A Primer of Methods in Biobehavioral Research: Improving a Study’s Design, Analysis, and Write Up

      • Joshua S. Talboom, Stephen G. West, Heather A. Bimonte-Nelson
      Pages 323-374

    14. Optimal Guidelines for Monitoring and Maintaining Rodent Health for Behavioral Research: What’s Right with My Rodent?

      • Joanne Tetens-Woodring
      Pages 375-403

  3. How? The Mazes: Protocols and Practice to Test Rodent Cognition

    1. Front Matter

      Pages 405-405
      Download chapter PDF

    2. General Water Escape Maze Testing Necessities and Guidelines for Rodents

      • Heather A. Bimonte-Nelson
      Pages 407-410

    3. The Water Radial-Arm Maze: Four Out of Eight Arms Platformed Protocol for Rodents

      • Heather A. Bimonte-Nelson
      Pages 411-419

    4. The Water Radial-Arm Maze: Seven Out of Eight Arms Platformed Protocol for Rodents

      • Heather A. Bimonte-Nelson
      Pages 421-427

    5. The Land Radial-Arm Maze: Eight Out of Eight Arms Baited with Food Protocol for Rodents

      • Jill M. Daniel
      Pages 429-432
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Keywords

About this book

This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, with every chapter delivering a comprehensive review of historical milestones in order to provide context for past discoveries, new findings, and future studies. Didactic foundations, operational definitions, and theory, as well as practical experimental and apparatus set-up, data analysis, and interpretation instructions are included in the first part of the book, while part two contains step-by-step protocols, troubleshooting, and tips from experts in the field.

Authoritative and inspirational, The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition serves as a detailed and practical manual for scientists wishing to implement these tools in their laboratories and for scholars interested in this powerful field.

Editors and Affiliations

  • Arizona State University, Tempe, USA

    Heather A. Bimonte-Nelson

Bibliographic Information

  • Book Title: The Maze Book

  • Book Subtitle: Theories, Practice, and Protocols for Testing Rodent Cognition

  • Editors: Heather A. Bimonte-Nelson

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-2159-1

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-2158-4Published: 11 March 2015

  • Softcover ISBN: 978-1-4939-5247-2Published: 08 October 2016

  • eBook ISBN: 978-1-4939-2159-1Published: 10 March 2015

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVIII, 457

  • Number of Illustrations: 29 b/w illustrations, 46 illustrations in colour

  • Topics: Neurosciences, Animal Models

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