Methods in Molecular Biology

RNA Interference

Challenges and Therapeutic Opportunities

Editors: Sioud, Mouldy (Ed.)

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  • Includes cutting-edge techniques in using RNA interference for therapeutic purposes
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-1538-5
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Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-1537-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-4891-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.

Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.

Table of contents (28 chapters)

Table of contents (28 chapters)
  • RNA Interference: Mechanisms, Technical Challenges, and Therapeutic Opportunities

    Sioud, Mouldy

    Pages 1-15

  • Nanostructured RNAs for RNA Interference

    Nakashima, Yuko (et al.)

    Pages 17-36

  • One Long Oligonucleotide or Two Short Oligonucleotides Based shRNA Construction and Expression

    Wang, Xue-jun (et al.)

    Pages 37-41

  • PLGA Microspheres Encapsulating siRNA

    Rosa, Giuseppe De, Ph.D. (et al.)

    Pages 43-51

  • Magnetic Nanoparticle and Magnetic Field Assisted siRNA Delivery In Vitro

    Mykhaylyk, Olga (et al.)

    Pages 53-106

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-1538-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-1537-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA in USD
  • ISBN 978-1-4939-4891-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
RNA Interference
Book Subtitle
Challenges and Therapeutic Opportunities
Editors
  • Mouldy Sioud
Series Title
Methods in Molecular Biology
Series Volume
1218
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-1538-5
DOI
10.1007/978-1-4939-1538-5
Hardcover ISBN
978-1-4939-1537-8
Softcover ISBN
978-1-4939-4891-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVI, 495
Number of Illustrations
50 b/w illustrations, 58 illustrations in colour
Topics