Mitochondrial Function in Lung Health and Disease
Editors: Natarajan, Viswanathan, Parinandi, Narasimham L. (Eds.)
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- About this book
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Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
- Table of contents (9 chapters)
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Role of Mitochondrial Reactive Oxygen and Nitrogen Species in Respiratory Diseases
Pages 1-25
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Regulation of Mitochondrial Functions by Transcription Factor NRF2
Pages 27-50
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Mitochondrion: A Missing Link in Asthma Pathogenesis
Pages 51-70
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ROS Signaling in Cardiovascular Dysfunction Associated with Obstructive Sleep Apnea
Pages 71-91
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Mitochondrial Excitation-Energy Coupling in Airway Smooth Muscle
Pages 93-116
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Table of contents (9 chapters)
- Download Preface 1 PDF (27.9 KB)
- Download Sample pages 1 PDF (534.5 KB)
- Download Table of contents PDF (1.4 MB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Mitochondrial Function in Lung Health and Disease
- Editors
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- Viswanathan Natarajan
- Narasimham L. Parinandi
- Series Title
- Respiratory Medicine
- Copyright
- 2014
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4939-0829-5
- DOI
- 10.1007/978-1-4939-0829-5
- Hardcover ISBN
- 978-1-4939-0828-8
- Softcover ISBN
- 978-1-4939-4436-1
- Series ISSN
- 2197-7372
- Edition Number
- 1
- Number of Pages
- XI, 222
- Number of Illustrations
- 10 b/w illustrations, 24 illustrations in colour
- Topics
