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Respiratory Medicine

Mitochondrial Function in Lung Health and Disease

Editors: Natarajan, Viswanathan, Parinandi, Narasimham L. (Eds.)

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  • Comprehensive, state-of-the-art review
  • Written by experts in the field
  • Covers both research and clinical issues
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  • ISBN 978-1-4939-0829-5
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About this book

Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.

Table of contents (9 chapters)

Table of contents (9 chapters)
  • Role of Mitochondrial Reactive Oxygen and Nitrogen Species in Respiratory Diseases

    Pages 1-25

    Anantha, Harijith, MD (et al.)

  • Regulation of Mitochondrial Functions by Transcription Factor NRF2

    Pages 27-50

    Reddy, Narsa M., PhD (et al.)

  • Mitochondrion: A Missing Link in Asthma Pathogenesis

    Pages 51-70

    Mabalirajan, Ulaganathan, MBBS, PhD (et al.)

  • ROS Signaling in Cardiovascular Dysfunction Associated with Obstructive Sleep Apnea

    Pages 71-91

    Kumar, Ganesh K., PhD (et al.)

  • Mitochondrial Excitation-Energy Coupling in Airway Smooth Muscle

    Pages 93-116

    Schaible, Niccole, MS (et al.)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-1-4939-0829-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
Softcover $159.00
price for USA in USD
Rent the eBook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondrial Function in Lung Health and Disease
Editors
  • Viswanathan Natarajan
  • Narasimham L. Parinandi
Series Title
Respiratory Medicine
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-0829-5
DOI
10.1007/978-1-4939-0829-5
Hardcover ISBN
978-1-4939-0828-8
Softcover ISBN
978-1-4939-4436-1
Series ISSN
2197-7372
Edition Number
1
Number of Pages
XI, 222
Number of Illustrations
10 b/w illustrations, 24 illustrations in colour
Topics