Gene Expression and Its Discontents

The Social Production of Chronic Disease

Authors: Wallace, Rodrick, Wallace, Deborah

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About this book

A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.

Table of contents (15 chapters)

Table of contents (15 chapters)

Buy this book

eBook $209.00
price for USA in USD (gross)
  • ISBN 978-1-4419-1482-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $269.00
price for USA in USD
  • ISBN 978-1-4899-8531-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Gene Expression and Its Discontents
Book Subtitle
The Social Production of Chronic Disease
Authors
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-1482-8
DOI
10.1007/978-1-4419-1482-8
Softcover ISBN
978-1-4899-8531-6
Edition Number
1
Number of Pages
IX, 227
Topics