Trace Elements in Man and Animals 10

1. Front Matter

   Pages i-xli

   PDF

2. Underwood Memorial Lecture

   1. Integrative Aspects of Zinc Metabolism and Function

      • Robert J. Cousins

      Pages 1-7

3. Cellular and Molecular Biology of Trace Elements

   1. Trace Elements Cellular Metabolims

      1. The Copper Transporting Atpases in Human Disease

         • Jonathan D. Gitlin

         Pages 9-13

      2. Regulation and Function of the Copper Ion Transport Machinery

         • Jaekwon Lee, Dennis J. Thiele

         Pages 15-20

      3. Control of Gene Expression of Glutathione Peroxidase-1 and Other Selenoproteins in Rats and Cultured Cells

         • Roger A. Sunde, Jacqueline K. Evenson

         Pages 21-27

      4. Cellular and Subcellular Distribution of Selenium and Selenium-Containing Proteins in the Rat

         • Dietrich Behne, Henning Pfeifer, Doris Röthlein, Antonios Kyriakopoulos

         Pages 29-34

      5. The Mechanism and Regulation of Zinc Transport in Yeast

         • David J. Eide

         Pages 35-41

      6. Metallothionein Faciltates Zinc Absorption in Zinc Deficient Mice but Limits Absorption in Zinc Replete Mice

         • P. Coyle, J. C. Philcox, A. M. Rofe

         Pages 43-46

      7. Metallothionein and Innate Activation of Primary Human and Mouse Monocytes

         • James Koropatnick, Suzanne Dale, Rudolfs K. Zalups

         Pages 47-50

      8. Role of Metallothionein on Zn, Cu, Cd, Au, and Ag Accumulation in Hepatic Cytosol of Heavy Metal-Injected Rats

         • S. Saito, K. Yoshida

         Pages 51-53

      9. Molecular Cloning of a Human cDNA Regulated by Heavy Metals

         • M. G. Pagliuca, S. Cigliano, R. Lerose, A. Leone

         Pages 55-58

      10. Distribution of Copper Transported ATP7B in Embryo and New Born Rat

          • T. Hosokawa, M. Okabe, M. Kurasaki, A. Hata, F. Endo, K. Nagano et al.

          Pages 59-61

      11. Interaction between Copper and Iron Metabolism in the Human Intestinal Caco-2 Cells

          • I. Gabrielli, Y. Sambuy, S. Ferruzza, M. L. Scarino

          Pages 63-64

      12. Induction of Metallothioneins by Zinc (Zn) Supplementation Quantification in Young Rat Tissues

          • G. S. Henriques, S. M. F. Cozzolino

          Pages 65-65

   2. Trace Elements and Oxidative Stress

      1. Iron, Oxidative Stress, the <i>HFE</i> Gene, and Lung Cancer

         • J. M. McCord, S. K. Bose, B. Gao

         Pages 67-70

      2. Selenium and the Protection Against Peroxynitrite

         • Helmut Sies, Lars-Oliver Klotz, Stefan M. Schieke, Karlis Briviba, Gavin E. Arteel

         Pages 71-76

      3. Cooperative Effects of Zinc / Selenium and Thiols in the Protection Against UV-Induced Genomic DNA Damage

         • Marie-Jeanne Richard, Nathalie Emonet-Piccardi, Christine Didier, Eric Jourdan, Marie-Thérèse Leccia, Marie-Odile Parat et al.

         Pages 77-82

      4. Trace Elements and Enzyme Redox Centers

         • Marc Fontecave

         Pages 83-87

      5. Importance of Trace Elements in Transcription Factor NF-κB Activation

         • Jacques Piette

         Pages 89-96

      6. Trace Elements

         • Y. Rayssiguier, A. Mazur

         Pages 97-103

Proceedings of the 10th International Symposium on Trace Elements in Man and Animals (TEMA 10), held May 2-7, 1999, in Evian, France.
This volume containing the proceedings of the tenth of the highly successful TEMA meetings, presents recent progress in the research on the functional role and metabolism of trace elements, and new developments in the understanding of molecular and cellular biology. Various contributions providing new data on zinc and copper transport mechanisms, enable a global view of the molecular metabolism of these metals in the human body, whilst other particularly dramatic results presented here offer new perspectives on the epidemiology of trace elements deficiency and supplementation. Also included are the results of recent major trials demonstrating the beneficial effect of selenium on human health. The spectacular growth of interest in the field of selenium, with the discovery of new selenoproteins and biological roles, is represented here along with the other areas of particular progress the research into boron and chromium, which have marked this year's meeting.

• diabetes
• metabolism
• physiology
• proteins
• transport

• Joseph Fourier University, Grenoble, France

  A. M. Roussel, A. E. Favier

• Beltsville Human Nutrition Research Center, Beltsville, USA

  R. A. Anderson

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