Mechanisms of Lymphocyte Activation and Immune Regulation II

Editors: Gupta, S. (Ed.)

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About this book

The ac ti vati on of Iymphocytes by physiologie ligands has become a central area of study for immunologists. Furthermore, Iymphocytes offer many advantages for the study of general aspects of receptor-mediated cellular activation. For these reasons, research on the cellular and molecular aspects of the activation of Iymphocytes by antigens, antigen analogues, Iymphokines and other growth factors has expanded enormously in the last several years. Aseries of conferences, "The International Conferences on Lymphocyte Activation", has been initiated to meet the growing need for a forum for the discussion of the topics that are included within the area of Iymphocyte activation. This volume represents the proceedings of the Second International Conference on Lymphocyte Activation and Immune Regulation, held on February 18-20, 1988 at Newport Beach, California. The proceedings comprise four major sections. The first deals with the T cell receptors and T cell activation. It includes a model for the T cell receptor interaction with a complex of MHC plus antigen, structure of y c'i T cell receptor and their distinct isotypic forms, the role of zeta chain in the expression and structure of T cell receptors and its role in transmembrane signalling. The use of somatic cell mutants in the study of signal transduction function of the T cell antigen receptors and the early and late steps of signal transduction via a / ß T cell antigen receptors are discussed.

Table of contents (17 chapters)

  • A Model for T Cell Receptor and MHC/Peptide Interaction

    Davis, Mark M. (et al.)

    Pages 13-16

  • Human T Cell Receptor γδ Structure

    Brenner, Michael B. (et al.)

    Pages 17-19

  • The Role of the Zeta Chain in the Expression, Structure and Function of the T Cell Receptor

    Klausner, Richard D. (et al.)

    Pages 21-24

  • Use of Somatic Cell Mutants to Study the Signal Transduction Function of the T Cell Antigen Receptor

    Goldsmith, Mark A. (et al.)

    Pages 25-33

  • Changes in Early and Late Steps of T Cell Activation by WT31 MoAb

    Gupta, Sudhir (et al.)

    Pages 35-42

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4757-5803-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4757-5805-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mechanisms of Lymphocyte Activation and Immune Regulation II
Editors
  • S. Gupta
Copyright
1989
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-5803-0
DOI
10.1007/978-1-4757-5803-0
Softcover ISBN
978-1-4757-5805-4
Edition Number
1
Number of Pages
158
Number of Illustrations and Tables
34 b/w illustrations
Topics