Cell Surface Receptors

A Short Course on Theory and Methods

Authors: Limbird, Lee E.

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About this book

The purpose of this book is to serve as a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying prin­ ciples is intended to remove the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, it is hoped that the basic concepts can be emphasized. This book is meant to be a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed. I feit compelled to write this book for several reasons. The primary philosophical reason was to provide, in one volume, an overall perspective on the study ofcell surface receptors that describes their characterization from pharmacological studies in a whole organ or tissue bath (chapter 2) to studies of radioligand binding in isolated membrane and detergent-solubilized pre­ parations (chapters 3-5) and, back again, to studies in intact cells or tissues using morphological and biochemical techniques (chapter 6). It is my opinion that the ultimate understanding of the molecular basis for hormone or drug­ receptor interactions, and the physiological consequences of these inter­ actions, will require an assessment of cell surface receptor function at all of these experimental levels. In many cases an investigator may not choose to of investigation considered here.

Table of contents (6 chapters)

Table of contents (6 chapters)

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-1-4757-1882-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $119.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Cell Surface Receptors
Book Subtitle
A Short Course on Theory and Methods
Authors
Copyright
1986
Publisher
Springer US
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-1-4757-1882-9
DOI
10.1007/978-1-4757-1882-9
Softcover ISBN
978-1-4757-1884-3
Edition Number
1
Number of Pages
XV, 196
Number of Illustrations
8 b/w illustrations
Topics