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The Pineal Gland and its Endocrine Role

  • Book
  • © 1983

Overview

Editors:
  1. J. Axelrod

    1. National Institute of Mental Health, Bethesda, USA

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  2. F. Fraschini

    1. University of Milan, Milan, Italy

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  3. G. P. Velo

    1. University of Verona, Verona, Italy

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Part of the book series: NATO Science Series A: (NSSA, volume 65)

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Table of contents (30 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introductory Lecture

    1. Regulation of Circadian Rhythms of Indoleamines in the Pineal Gland

      • Julius Axelrod
      Pages 1-13

  4. Biochemistry

    1. Pteridines in the Pineal and Effects of These Substances on the Indole Metabolism of This Organ

      • I. Ebels, M. G. M. Balemans, J. van Benthem, H. P. J. M. Noteborn, A. de Morée
      Pages 151-178

    2. Peptidic and Proteic Substances Isolated from Pineals and Their Relation to the Hypophysial-Hypothalamic-Gonadal Axis

      • I. Ebels
      Pages 179-198

    3. Molecular Aspects of Neuroendocrine Integrative Processes in the Pineal Gland

      • D. P. Cardinali, Mónica N. Ritta, María I. Vacas, P. R. Lowenstein, P. V. Gejman, C. González Solveyra et al.
      Pages 199-219

    4. The Responses of Melatonin Rhythms to Environmental Lighting

      • R. J. Wurtman, M. H. Deng, P. Ronsheim
      Pages 221-226

    5. The Role of Light and Age in Determining Melatonin Production in the Pineal Gland

      • Russel J. Reiter
      Pages 227-241

    6. Differential Regulation of the 24 Hour Pattern of Serum Melatonin and N-Acetylserotonin

      • G. M. Brown, L. J. Grota, L. Harvey, H. W. Tsui, S. F. Pang
      Pages 243-256

  5. Physiology

    1. Differential Localization of Melatonin and N-Acetylserotonin in Brain

      • G. M. Brown, O. Pulido, L. P. Niles, S. Psarakis, A. Porietis, G. A. Bubenik et al.
      Pages 257-276

    2. Melatonin Action: Sites and Possible Mechanisms in Brain

      • D. P. Cardinali, María I. Vacas, María I. Keller Sarmiento, E. Morguenstern
      Pages 277-301

    3. Seasonal Reproductive Events Related to the Pineal Gland

      • Russel J. Reiter
      Pages 303-316

    4. Melatonin as the Hormone Which Mediates the Effects of the Pineal Gland on Neuroendocrine-Reproductive Axis of the Syrian Hamster

      • Russel J. Reiter
      Pages 317-330

    5. The 5-Methoxyindoles Different from Melatonin: Their Effects on the Sexual Axis

      • Paul Pévet
      Pages 331-348

    6. Actions of the Pineal Gland and Melatonin on the Secretion of Cerebrospinal Fluid

      • W. B. Quay
      Pages 349-360
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Keywords

About this book

The pineal gland has been a subject of interest and speculation for more than 2000 years. Greek anatomists were impressed by the ob­ servation that the pineal gland is an unpaired structure and they believed that it regulated the flow of thoughts. The philosopher Descartes proposed an important role for this organ in brain function. At the beginning of the 20th century experiments by several investi­ gators indicated that the pineal influenced sexual function and skin pigmentation and was also responsive to light signals. With the iso­ lation of melatonin from bovine pineal glands by Lerner and cowork­ ers in 1958 the modern era of pineal research was initiated. Within a few years the pathway for the biosynthesis of melatonin in the pineal was elucidated. Soon thereafter it was shown that the formation of melatonin was influenced by environmental lighting. Ana­ tomists found that the pineal was innervated by sympathetic nerves and that the gland had photoreceptor elements. It was also shown that the gonads were influenced by light via the pineal gland. Research on the pineal gland became of increasing interest to anatomists, bioche­ mists, pharmacologists and endocrinologists. With the expanding know­ ledge concerning the function of the pineal gland contributed by the wide variety of disciplines, it was thought that a study workshop would be timely.

Editors and Affiliations

  • National Institute of Mental Health, Bethesda, USA

    J. Axelrod

  • University of Milan, Milan, Italy

    F. Fraschini

  • University of Verona, Verona, Italy

    G. P. Velo

Bibliographic Information

  • Book Title: The Pineal Gland and its Endocrine Role

  • Editors: J. Axelrod, F. Fraschini, G. P. Velo

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4757-1451-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1983

  • Softcover ISBN: 978-1-4757-1453-1Published: 23 May 2013

  • eBook ISBN: 978-1-4757-1451-7Published: 01 December 2013

  • Edition Number: 1

  • Number of Pages: IX, 604

  • Topics: Neurosciences

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