Alcohol and Aldehyde Metabolizing Systems-IV

Enzymology of Alcohol and Aldehyde Dehydrogenases and Cytochrome P-450

1. Role of Hydroxyl Radicals in Microsomal Oxidation of Alcohols

   • Arthur I. Cederbaum, Elisa Dicker, Gerald Cohen

   Pages 1-10

2. On the Possible Relationship of Cytochrome P-450 to Alcohol Metabolism: Fundamental Aspects of the Microsomal Hydroxylation System, Including Properties and Interactions of the Components

   • M. J. Coon, A. V. Persson, J. S. French

   Pages 11-22

3. Evolution of Aldehyde Reductase: An Immunological Approach to the Relatedness of Aldehyde Reductase from Different Species

   • W. S. Davidson, T. G. Flynn

   Pages 23-30

4. Isozymes of Alcohol Dehydrogenase and Aldehyde Dehydrogenase in Japanese and their Role in Alcohol Sensitivity

   • Shoji Harada, Dharam P. Agarwal, H. Werner Goedde

   Pages 31-39

5. On the Interaction of Human Liver Aldehyde Dehydrogenase E1 Isoenzyme with Disulfiram and Iodoacetamide

   • John D. Hempel, Robert C. Vallari, Regina Pietruszko

   Pages 41-49

6. Ethanol-Inducible Liver Cytochrome P-450 in the Rat: Relative Specificity for Ethanol Oxidation Activity in Vitro

   • A. M. Mungikar, C. Hetu, J.-G. Joly

   Pages 51-56

7. Genetic Regulation of Alcohol Dehydrogenase, Aldehyde Dehydrogenase and Aldehyde Oxidase Isozymes in the Mouse

   • Roger S. Holmes

   Pages 57-66

8. Isozymes of Alcohol Dehydrogenases

   • Hans Jörnvall

   Pages 67-76

9. Carbon-13 Magnetic Resonance Probe of Coenzyme and Inhibitor Binding in Liver Alcohol Dehydrogenase

   • Douglas T. Jones, Raja G. Khalifah

   Pages 77-83

10. Properties of Adlehyde Dehydrogenase from Chemically-Induced Rat Hepatomas and Normal Rat Liver

    • Ronald Lindahl

    Pages 85-93

11. Kinetic Isotope Effects in Cytochrome P-450-Catalyzed Oxidation Reactions. II. Interactions of Cytochrome P-450 with Substrates and Nadph-Cytochrome \(\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{c} \) Reductase

    • Anthony Y. H. Lu, Gerald T. Miwa, Susan B. West, Barbara J. Hodshon, William A. Garland

    Pages 95-108

12. Alterations of Hepatic Alcohol Metabolizing Enzyme Activities Due to Thyroid Hormones

    • F. Moreno, M. Minzlaff, K. H. Hauptmeier, R. Teschke

    Pages 109-115

13. Genetically Mediated Responses of Microsomal Ethanol Oxidation in Mice

    • Dennis R. Petersen, Neal Atkinson

    Pages 117-128

14. In Vivo Evaluation of Ambivalent Active-Site-Directed Inactivators of Liver Alcohol Dehydrogenase

    • Wen-Sherng Chen, David P. Bohlken, Bryce V. Plapp

    Pages 129-135

15. Kinetic and Mechanistic Studies of Oxidation of Vitamin a Alcohol to Vitamin a Aldehyde by Horse Liver Alcohol Dehydrogenase. The Inhibition by Ethanol and Pyrazole

    • Y. Pocker, K. W. Raymond

    Pages 137-150

16. Mechanism of Inhibition of Mixed-Function Oxidation by Ethanol

    • Lester A. Reinke, Steven A. Belinsky, Frederick C. Kauffman, Ronald G. Thurman

    Pages 151-161

17. Multifunctionality of Liver Alcohol Dehydrogenase

    • C. S. Tsai

    Pages 163-172

18. The Nature and Function of Aldehyde Reductases from Rat Brain

    • Anthony J. Turner, Susan R. Whittle

    Pages 173-180

19. Mechanism of the Magnesium Ion Activation of the Catalytic Activity of Horse Liver Aldehyde Dehydrogenase

    • Kojiro Takahashi, Carolyn S. Brown, Henry Weiner

    Pages 181-188