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Guanidines

Historical, Biological, Biochemical, and Clinical Aspects of the Naturally Occurring Guanidino Compounds

  • Book
  • © 1985

Overview

Editors:
  1. Akitane Mori

    1. Inst. for Neurobiology, Okayama University Medical School, Okayama 700, Japan

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  2. B. D. Cohen

    1. The Bronx Lebanon Hospital Center, Bronx, USA

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  3. A. Lowenthal

    1. Laboratory of Neurochemistry, Born-Bunge Foundation, Universitaire Instelling Antwerpen, Wilrijk, Belgium

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Table of contents (38 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Analytical Method for Guanidino Compounds

    1. Front Matter

      Pages 1-1
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    2. New High-Speed Fully Automated Guanidino Compound Analyzer

      • Sakae Higashidate, Tetsuya Maekubo, Muneo Saito, Masaaki Senda, Tadao Hoshino
      Pages 3-13

    3. Automatic Guanidine Analyzer Using Benzoin as a Fluorogenic Reagent

      • Yiau-Lin Huang, Masaaki Kai, Yosuke Ohkura
      Pages 15-31

    4. Simple Methods for the Determination of Methylguanidine and Guanidinosuccinic Acid in Biological Fluids

      • Toshiyuki Nakao, Seiji Fujiwara, Tadashi Miyahara
      Pages 33-38

    5. Enzymic Determination of Methylguanidine in Urine

      • Motoo Nakajima, Kazuo Nakamura, Yoshio Shirokane
      Pages 39-46

  3. Metabolism of Guanidino Compound in Normal and Abnormal Organs, and in Metabolic Diseases

    1. Front Matter

      Pages 47-47
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    2. Developmental Changes in Guanidino Compounds Levels in Mouse Organs

      • Yoko Watanabe, Shoichiro Shindo, Akitane Mori
      Pages 49-58

    3. Developmental Changes of Guanidino Compounds in Chick Embryo

      • Yoko Watanabe, Takashi Kadoya, Masayoshi Fukui, Rei Edamatsu, Akitane Mori, Sonoko Seki
      Pages 59-69

    4. Metabolism of L-[Amidino-15N]-Arginine to Guanidino Compounds

      • Shoichiro Shindo, Akitane Mori
      Pages 71-81

    5. Biosynthesis of Guanidinoacetic Acid in Isolated Rat Hepatocytes

      • Kazumasa Aoyagi, Shoji Ohba, Mitsuhiro Miyazaki, Sohji Nagase, Satomi Iida, Mitsuharu Narita et al.
      Pages 83-92

    6. Biosynthesis of Guanidinosuccinic Acid in Isolated Rat Hepatocytes: Evaluation of Guanidine Cycle and Acidosis

      • Kazumasa Aoyagi, Shoji Ohba, Mitsuhiro Miyazaki, Sohji Nagase, Satomi Iida, Mitsuharu Narita et al.
      Pages 93-103

    7. The Role of the Liver as a Significant Modulator of the Serum Guanidinoacetic Acid Level in Man

      • Hiroaki Muramoto, Yohei Tofuku, Mitsuhiko Kuroda, Ryoyu Takeda
      Pages 105-112

    8. Conversion of Urea Nitrogen into Protein Nitrogen by a Freshwater Fish, Sarotherodon Mossambicus

      • K. C. Chitra, K. S. Swami, K. S. Jagannatha Rao
      Pages 113-118

    9. Topographical Distribution of Sheep Brain Arginase: Its Response to Some Guanidino Compounds

      • V. Mohanachari, K. Satyavelu Reddy, K. Indira, K. S. Swami
      Pages 119-124

    10. The Effect of Sodium Valproate on Blood Ammonia Levels and the Concentrations of Guanidino Compounds in Mouse Tissue

      • Jium Shiou Chang, Yoko Watanabe, Akitane Mori
      Pages 125-133

    11. The Guanidine Cycle

      • Harini Patel, Burton D. Cohen
      Pages 135-144

    12. Arginine Utilization in Muscle and Kidney of Frog during Ammonotoxemia

      • P. Neeraja, K. S. Swami
      Pages 145-148

    13. Arginine Metabolism in Citrullinemic Patients

      • Takeyori Saheki, Mariko Sase, Kyoko Nakano, Yukio Yagi
      Pages 149-158

    14. Studies on the Occurrence of Guanidino Compounds in Serum and Urine of Patients with Epilepsy, Neuronal Ceroid-Lipofuscinosis and Uremic Patients

      • Claus Munk Plum
      Pages 159-169
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Keywords

About this book

In 1978, we had the first research meeting of guanidine compound analysis in Okayama, Japan. The purpose of the meeting was to standardize the methods of analyzing guanidino compounds, because the analytic methods, even, for example, that of normal plasma, were quite different from laboratory to laboratory at that time. More than ten laboratories joined in this research project. Thereafter, the purpose of the annual meetings was extended to cover general biochemistry of guanidino compounds, and every meeting has served to promote our mutual growth and progress. The last meeting of the Japan Guanidino Compounds Research Association in 1982 brought together more than 80 members, and about 30 papers were presented there. This, the 6th annual meeting, brings the International Symposium on Guani­ dino Compounds here to Tokyo. Recently, many scientists are engaged in the research of guanidine compounds, especially in the field of clinical bio­ chemistry. I am sure that the observation of guanidinosuccinic acid in the urine of uremic patients by Dr. Cohen's research group in 1963 ignited the recent exploration of the role of guanidino compounds in renal diseases. The study of guanidino compounds does, however, have a long history. The first knowledge of guanidine was obtained by Strecker in 1861 (Annalen der Chemie und Pharmacie, 118, 151- 177, 1981).

Editors and Affiliations

  • Inst. for Neurobiology, Okayama University Medical School, Okayama 700, Japan

    Akitane Mori

  • The Bronx Lebanon Hospital Center, Bronx, USA

    B. D. Cohen

  • Laboratory of Neurochemistry, Born-Bunge Foundation, Universitaire Instelling Antwerpen, Wilrijk, Belgium

    A. Lowenthal

Bibliographic Information

  • Book Title: Guanidines

  • Book Subtitle: Historical, Biological, Biochemical, and Clinical Aspects of the Naturally Occurring Guanidino Compounds

  • Editors: Akitane Mori, B. D. Cohen, A. Lowenthal

  • DOI: https://doi.org/10.1007/978-1-4757-0752-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1985

  • Softcover ISBN: 978-1-4757-0754-0Published: 26 March 2013

  • eBook ISBN: 978-1-4757-0752-6Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XVI, 479

  • Number of Illustrations: 41 b/w illustrations

  • Topics: Biochemistry, general, Organic Chemistry

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