Advances in Experimental Medicine and Biology

Purine Metabolism in Man-IV

Part B: Biochemical, Immunological, and Cancer Research

Editors: De Bruyn, Chris H. (Ed.)

Free Preview

Buy this book

eBook $99.00
price for USA in USD
  • ISBN 978-1-4757-0390-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $129.00
price for USA in USD
About this book

These two volumes, entitled "Purine Metabolism in Man IV" con­ tain the papers presented at the Fourth International Symposium on Human Purine and Pyrimidine Metabolism", held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet­ ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo­ lism under normal and pathological conditions has been growing rapid­ ly. Apart from the more or less classical topics such as hyperuricae­ mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse­ quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting mych new data on both issues have been re­ ported which indicate clear differences in the pathways of ATP metabo­ lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel­ oped.

Table of contents (96 chapters)

Table of contents (96 chapters)
  • Evidence of a New Type Of Phosphoribosylpyrophosphate Synthetase With Abnormal Kinetic Properties in Hyperuricemias

    Pages 1-4

    Mousson, B. (et al.)

  • Radioimmunoassay Studies of Human Phosphoribosylpyrophosphate Synthetase

    Pages 5-10

    Becker, Michael A. (et al.)

  • Synthesis of (14C)-Ribose-5-Phosphate and (14C)-Phosphoribosyl-Pyrophosphate and Their use in New Enzyme Assays

    Pages 11-13

    Boss, Gerry R. (et al.)

  • Purine Synthesis During Amino Acid Starvation of Lymphoblasts With HPRT Deficiency or PP-Ribose-P Synthetase Overactivity Decreases Less Than in Normal Cells

    Pages 15-19

    Boss, Gerry R.

  • Purine Synthesis and Salvage in Brain and Liver

    Pages 21-26

    Allsop, Jennifer (et al.)

Buy this book

eBook $99.00
price for USA in USD
  • ISBN 978-1-4757-0390-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $129.00
price for USA in USD
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Purine Metabolism in Man-IV
Book Subtitle
Part B: Biochemical, Immunological, and Cancer Research
Editors
  • Chris H. De Bruyn
Series Title
Advances in Experimental Medicine and Biology
Series Volume
165
Copyright
1984
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-0390-0
DOI
10.1007/978-1-4757-0390-0
Softcover ISBN
978-1-4757-0392-4
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVI, 520
Topics