Advances in Experimental Medicine and Biology

Cellular Ca2+ Regulation

Editors: Pfeiffer, D. (Ed.)

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About this book

This book arose from a meeting held at the University of Washington, Seattle, in July of 1986. The meeting was a satellite symposium of the XXXth International Congress of Physiological Sciences which occurred in Vancouver, canada, at that time. 2 Adjustments in the cytoplasmic Ca + concentration of cells occur in response to a variety of external signals. These fluctuations are a cen­ tral component of one mechanism by which cells adapt their activities to changes in the external environment and to the requirements of whole body 2 homeostatic mechanisms. It is now clear that redistribution of Ca + within 2 intracellular compartments, as well as changes in the rates of Ca + influx and extrusion at the whole cell level, occur during signal-dependent 2 changes in the cytoplasmic Ca + concentration. In summarizing current research in this area, this volume considers first the properties of indi­ vidual cation transporting activities located in various cell membranes. It then moves to the cellular level, where the consequence of individual transporting activities acting in concert is examined. l!D.phasis is also 2 p1 aced on pa tho1 ogica1 conditions which resu1 t in loss of cell Ca + regu1 a­ tion as a part of the disease process. We hope that this approach will help the reader to integrate developments in this large and rapdi1y changing fie1 d.

Table of contents (27 chapters)

Table of contents (27 chapters)
  • Mechanisms of Mitochondrial Calcium Transport

    Pages 1-14

    Gunter, Thomas E. (et al.)

  • Permeability Pathways of Ca2+ Efflux from Mitochondria: H+ Specificity and Reversibility of the Permeability Defect

    Pages 15-23

    Pfeiffer, Douglas R. (et al.)

  • The Role of Calcium and Phospholipase A2 in Glucagon-Induced Enhancement of Mitochondrial Calcium Retention

    Pages 25-36

    Hoek, Jan B. (et al.)

  • Sodium/Proton Antiporters in the Mitochondrial Inner Membrane

    Pages 37-46

    Garlid, Keith D.

  • Monovalent Cation Antiport Reactions in Isolated Mitochondria

    Pages 47-57

    Brierley, Gerald P. (et al.)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-1-4757-0007-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Cellular Ca2+ Regulation
Editors
  • D. Pfeiffer
Series Title
Advances in Experimental Medicine and Biology
Series Volume
232
Copyright
1988
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-0007-7
DOI
10.1007/978-1-4757-0007-7
Softcover ISBN
978-1-4757-0009-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
IX, 273
Number of Illustrations
24 b/w illustrations
Topics