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Advances in Experimental Medicine and Biology

Proteins Involved in DNA Replication

Editors: Huebscher, Ulrich (Ed.)

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About this book

This book collects the Proceedings of a workshop sponsored by the European Molecular Biology Organization (EMBO) entitled "Pro­ teins Involved in DNA Replication" which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland. The aim of this workshop was to review and discuss the status of our knowledge on the intricate array of enzymes and proteins that allow the replication of the DNA. Since the first discovery of a DNA polymerase in Escherichia coli by Arthur Kornberg twenty eight years ago, a great number of enzymes and other proteins were des­ cribed that are essential for this process: different DNA poly­ merases, DNA primases, DNA dependent ATPases, helicases, DNA liga­ ses, DNA topoisomerases, exo- and endonucleases, DNA binding pro­ teins and others. They are required for the initiation of a round of synthesis at each replication origin, for the progress of the growing fork, for the disentanglement of the replication product, or for assuring the fidelity of the replication process. The number, variety and ways in which these proteins inter­ act with DNA and with each other to the achievement of replication and to the maintenance of the physiological structure of the chromo­ somes is the subject of the contributions collected in this volume. The presentations and discussions during this workshop reinforced the view that DNA replication in vivo can only be achieved through the cooperation of a high number of enzymes, proteins and other cofactors.

Table of contents (43 chapters)

  • Enzyme Studies of Replication of the Escherichia Coli Chromosome

    Kornberg, Arthur

    Pages 3-16

  • Enzymological Studies of the T4 Replication Proteins

    Jongeneel, C. Victor (et al.)

    Pages 17-33

  • In Vitro Replication of Bacteriophage Φ29

    Salas, Margarita (et al.)

    Pages 35-44

  • Proteins and Nucleotide Sequences Involved in DNA Replication of Filamentous Bacteriophage

    Geider, K. (et al.)

    Pages 45-54

  • In Vitro Replication of Rl Miniplasmid DNA

    Diaz, Ramon (et al.)

    Pages 55-61

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-1-4684-8730-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-1-4684-8732-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Proteins Involved in DNA Replication
Editors
  • Ulrich Huebscher
Series Title
Advances in Experimental Medicine and Biology
Series Volume
179
Copyright
1984
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-8730-5
DOI
10.1007/978-1-4684-8730-5
Softcover ISBN
978-1-4684-8732-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XII, 571
Topics