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Nato Science Series B:

Vascular Endothelium

Receptors and Transduction Mechanisms

Editors: Catravas, J. (Ed.)

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eBook $84.99
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  • ISBN 978-1-4684-8532-5
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Softcover $109.00
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About this book

Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now firmly established as active and essential participants in a host of crucial physiological and pathophysiological functions. Probably the two most important factors responsible for promoting the current knowledge of endothelial functions are 1) observations in the late sixties-early seventies that many non-ventilatory properties of the lung could be attributed to the pulmonary endothelium and 2) the establishment, in the early and mid-seventies of procedures for routine culture of vascular endothelial cells. Many of these endothelial functions require the presence of receptors on the surface of the plasma membrane. There is now evidence for the existence among others of muscarinic, a-and /3-adrenergic, purine, insulin, histamine, bradykinin, lipoprotein, thrombin, paf, fibronectin, vitronectin, interleukin and albumin receptors. For some of these ligands, there is evidence only for the existence of endothelial binding sites. Traditionally, agonist binding must elicit a response for the binding site to be considered a receptor and, in some cases, the nature of the response resulting from the interaction of a substance with the endothelium remains unclear. It is beyond the scope of this introduction to even enumerate the various endothelial homeostatic processes. This monograph contains the proceedings of the Advanced Studies Institute on "Vascular Endothelium: Receptors and Transduction Mechanisms" held in Porto Carras, Greece from June 18-29, 1988.

Table of contents (24 chapters)

  • Structural Basis for Endothelial Cell Function: Role of Calcium, Polyphosphoinositide Turnover and G-Proteins

    Ryan, Una S.

    Pages 3-20

  • Modulation of Endothelial Permeability: Role of Receptors, Second Messengers and Ion Channels

    Olesen, Søren-Peter

    Pages 21-27

  • Factors Affecting the Fluidity of the Endothelial Cell Plasma Membrane

    Block, Edward R.

    Pages 29-42

  • Vascular Endothelial Surface Proteins in the Perfused Rabbit Lung

    Gillis, C. Norman (et al.)

    Pages 43-54

  • Endothelial Specific Binding Sites for Permeant Plasma Macromolecules: Albumin Binding Proteins

    Simionescu, Nicolae (et al.)

    Pages 55-66

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-8532-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-8534-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Vascular Endothelium
Book Subtitle
Receptors and Transduction Mechanisms
Editors
  • J. Catravas
Series Title
Nato Science Series B:
Series Volume
308
Copyright
1989
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-8532-5
DOI
10.1007/978-1-4684-8532-5
Softcover ISBN
978-1-4684-8534-9
Series ISSN
0258-1221
Edition Number
1
Number of Pages
XII, 308
Number of Illustrations and Tables
65 b/w illustrations
Topics