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Carbohydrate Metabolism in Cultured Cells

Editors: Morgan, M.J. (Ed.)

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About this book

It is perhaps obvious to any student of Biology that the discovery of chemical processes in whole organisms has usually preceded the elucidation of the compo­ nent steps. However, it is perhaps less obvious that the unravelling of the se­ quences in which those chemical steps occur in living matter, of the precise mechanisms involved, and of the manner in which they are regulated, would have been achieved neither by the study of intact plants and animals nor even of extracts derived from them. Our ability to understand the nature and regulation of metabolism rests on two main premises: the postulate that life processes can indeed be validly investigated with individual cells and cell-free extracts, and the thesis that there is an essential "unity in biochemistry" (as Kluyver put it, 60 years ago) that enables events in one organism to be legitimately studied in another. Of particular utility in this latter respect has been the use of cultures of single-celled organisms, growing in defined media-especially prokaryotes, such as Escherichia coli, and eukaryotes, such as Neurospora and Sac­ charomyces sp. , to which both biochemical and genetical techniques could be applied. It was, of course, Pasteur's observations of bacterial fermentations that first overthrew the belief that oxygen was essential for all energy-yielding pro­ cesses: his recognition that "La fermentation . . . . . c' est La vie sans air" laid the foundations of our knowledge of glycolysis.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Studies of Regulation of Hexose Transport into Cultured Fibroblasts

    Pages 1-27

    Kalckar, Herman M. (et al.)

  • The Utilization of Carbohydrates by Animal Cells

    Pages 29-75

    Morgan, Michael J. (et al.)

  • Biochemical Genetics of Respiration-Deficient Mutants of Animal Cells

    Pages 77-109

    Scheffler, Immo E.

  • Glutaminolysis in Animal Cells

    Pages 111-150

    McKeehan, Wallace L.

  • The Metabolism and Utilization of Carbohydrates by Suspension Cultures of Plant Cells

    Pages 151-181

    Stepan-Sarkissian, Gagik (et al.)

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-7679-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.99
price for USA in USD
  • ISBN 978-1-4684-7681-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Carbohydrate Metabolism in Cultured Cells
Editors
  • M.J. Morgan
Copyright
1986
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-7679-8
DOI
10.1007/978-1-4684-7679-8
Softcover ISBN
978-1-4684-7681-1
Edition Number
1
Number of Pages
536
Number of Illustrations
18 b/w illustrations
Topics