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Neonatal Jaundice

New Trends in Phototherapy

Editors: Rubaltelli, Firmino F. (Ed.)

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About this book

Hyperbilirubinemia of the neonate and the related risk of brain damage with conseguent important alterations in motor development, particularly in sick preterm babies, remains a major problem in nurseries throughout the world. Since its introduction in the 1950's phototherapy has been used for reducing serum bilirubin concentrations in the newborn with hyperbilirubinemia; however, only recently the photoprocesses invoked by light on various substrates including bilirubin have been clari­ fied in sufficient detail. Light treatment actually exemplifies the intimate relationship between the clinical and basic sciences: the better understanding of the mechanism of phototherapy as a result of investigations initiated in the laboratory has been extended to the bedside as new types of lamps or new schedules of treatment. As a consequence, phototherapy of hyperbilirubinemia has emerged as a well-established branch of photomedicine, based on molecular photo­ biology, scientific method, and creative use of physics and sophis­ ticated electrooptical capabilities. The collaboration and exchange of information between workers in different basic and clinical di­ sciplines is likely to stimulate a further optimization of photo­ therapy. The purpose of this monograph is to discuss some of the new aspects of bilirubin metabolism and phototherapeutic treatment. Bilirubin conjugation in the fetal and early neonatal life, the mechanism of bilirubin entry into the brain, the measurements of bilirubin concentration in the skin and serum bilirubin binding capacity are discussed by a number of prominent neonatologists.

Table of contents (28 chapters)

Table of contents (28 chapters)
  • Bilirubin Metabolism in the Newborn: Its Mechanisms and Relationship to Kernicterus

    Pages 1-12

    Stern, Leo

  • Serum Bilirubin Mono- and Diconjugates in Human Newborns

    Pages 13-21

    Muraca, Maurizio (et al.)

  • Mechanism of Bilirubin Entry into the Brain in an Animal Model

    Pages 23-34

    Bratlid, Dag

  • The Importance of Serum Binding and the Blood Brain Barrier in the Development of Acute Bilirubin Neurotoxicity

    Pages 35-43

    Wennberg, Richard P. (et al.)

  • Distribution of Bilirubin between Serum and Cerebrospinal Fluid in Newborn Infants

    Pages 45-49

    Meisel, P. (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4684-7517-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.99
price for USA in USD
  • ISBN 978-1-4684-7519-7
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neonatal Jaundice
Book Subtitle
New Trends in Phototherapy
Editors
  • Firmino F. Rubaltelli
Copyright
1984
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-7517-3
DOI
10.1007/978-1-4684-7517-3
Softcover ISBN
978-1-4684-7519-7
Edition Number
1
Number of Pages
XI, 321
Number of Illustrations
87 b/w illustrations
Topics

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