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  • © 1978

Gastrointestinal Hormones and Pathology of the Digestive System

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 106)

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Table of contents (40 chapters)

  1. Front Matter

    Pages i-x
  2. A Short History of Digestive Endocrinology

    • M. I. Grossman
    Pages 5-10
  3. Endocrine Cells of the Gastrointestinal Tract: General Aspects, Ultrastructure and Tumour Pathology

    • E. Solcia, C. Capella, R. Buffa, L. Usellini, P. Fontana, B. Frigerio
    Pages 11-22
  4. Peptidergic Innervation of the Gastrointestinal Tract

    • J. M. Polak, S. R. Bloom
    Pages 27-49
  5. Polypeptides of the Amphibian Skin Active on the Gut and Their Mammalian Counterparts

    • V. Erspamer, P. Melchiorri, C. Falconieri Erspamer, L. Negri
    Pages 51-64
  6. The Gastrins: Structure and Heterogeneity

    • R. A. Gregory
    Pages 75-83
  7. Different Forms of Gastrin in Peptic Ulcer

    • G. J. Dockray, I. L. Taylor
    Pages 91-96
  8. Antral G Cells and Mucosal Gastrin Concentration in Normal Subjects and in Patients with Duodenal Ulcer

    • L. Barbara, G. Biasco, M. Salera, F. Baldi, G. Di Febo, M. Miglioli
    Pages 97-104
  9. Cimetidine Treatment in Zollinger-Ellison Syndrome

    • S. Bonfils, M. Mignon, G. Kloeti
    Pages 111-116
  10. Calcitonin, Parathyroid Hormone and Insulin Concentrations in Sera from Patients with Gastrinoma

    • M. Cecchettin, A. Albertini, G. Bonora, P. Vezzadini
    Pages 117-119
  11. Trophic Effects of Endogenous and Exogenous Pancreozymin Upon the Exocrine and Endocrine Pancreas

    • T. Fujita, Y. Matsunari, Y. Koga, K. Sato, M. Hayashi
    Pages 147-150
  12. Enteropancreatic Axis

    • S. R. Bloom, J. M. Polak
    Pages 151-163

About this book

The discovery that the same or similar peptides are present in endocrine cells and in neurons is one of the most exciting and provocative recent developments in biology. Suddenly neurophysiologists and endocrinologists have found that they have a great deal to discuss with each other. Substances originally isolated as hypothalamic hormones turn out to be abundantly present in neurons of other parts of the brain and in endocrine cells and neurons of the gut and pancreas. Similarly, substances originally isolated as gut hormones are found not only in gut endocrine cells but also in gut neurons and in brain neurons. It turns out that the group of peptides that we are accustomed to call gastrointestinal hormones are not all confined to the gastrointestinal tract and are not all solely hormones. We are learning that the chemical transmitters of the neurocrine, endocrine, and paracrine systems form a single group of related substances. This volume contains the latest installments in this fascinating story. It tells how these pep tides were isolated and their amino acid sequences determined, how the heterogeneity of most, perhaps all, of these peptides is being revealed as variant forms of them are discovered, how antibodies to these peptides are used as powerful tools to measure their concentrations in body fluids and to localize the cells in which they are synthesized and stored, and, finally, how the role of these substances in normal physiology and in pathological states is being unraveled.

Editors and Affiliations

  • Veterans Administration, Wadsworth Hospital Center, Los Angeles, USA

    Morton Grossman

  • Institute of 3rd Surgical Pathology, University of Rome, Italy

    V. Speranza, N. Basso, E. Lezoche

Bibliographic Information

  • Book Title: Gastrointestinal Hormones and Pathology of the Digestive System

  • Editors: Morton Grossman, V. Speranza, N. Basso, E. Lezoche

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7248-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4684-7250-9Published: 31 July 2013

  • eBook ISBN: 978-1-4684-7248-6Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 326

  • Number of Illustrations: 32 b/w illustrations

  • Topics: Gastroenterology

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access