Nato Science Series A:

The Molecular Basis of B-Cell Differentiation and Function

Authors: Ferrarini, M., Pernis, Benventuto

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About this book

The progress in protein and nucleic acid chemistry together with improvements of the previously employed tissue culture techniques have led to the solution of problems such as that of the generation of antibody diversity or of the molecular structure of T and B cell membrane receptor for antigen which had challenged the past generations of immunologists. Thanks to this progress an impressive amount of knowledge has been accumulated on certain cell types that were relatively "mysterious" until recently. The B lymphocyte represents a typical example of such a cell. With these considerations in mind, we have started to organize a NATO summer school on "The molecular basis of B cell differentation and function" that had the specific aim of bringing up to date a selected number of young investigators. During the course, held in Santa Margheri ta Ligure, October 1-11, 1985 it became apparent that rather than a formal school we had organized an informal series of Workshops where both the Faculty members and the participants were discussing their own data in addition to reviewing the general progress in the field. The deep commi ttment of everyone to his research subj ect and the enthusiasm had caused this very successful change in the shape of the course. At the end we asked the members of the Faculty and the participants to write a summary of their data and of their point of view on selected subj ect s.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • Regulation of the Assembly and Expression of Immunoglobulin Genes: Variable Region Assembly and Heavy Chain Class Switching

    Pages 1-17

    DePinho, R. A. (et al.)

  • Acquired Alterations Around the Cε Gene in Cultured Mouse Myeloma Cells

    Pages 19-21

    Calvo, Charles-Félix (et al.)

  • Differentiation in the I.29 B Cell Lymphoma: Precommitment to IgA or IgE Switch in Individual IgM

    Pages 23-28

    Sitia, R. (et al.)

  • Transcriptional and Post-Transcriptional Control of Ig-Gene Expression in Murine B-Cells Activated by LPS and Anti-Receptor Antibodies

    Pages 29-32

    Chen-Bettecken, Una (et al.)

  • Restricted Set of V Genes and Extensive Idiotype Crossreactivity of Autoantibodies

    Pages 33-39

    Monestier, Marc (et al.)

Buy this book

eBook $64.99
price for USA in USD
  • ISBN 978-1-4684-7035-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $84.99
price for USA in USD
  • ISBN 978-1-4684-7037-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
The Molecular Basis of B-Cell Differentiation and Function
Authors
Series Title
Nato Science Series A:
Series Volume
123
Copyright
1986
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-7035-2
DOI
10.1007/978-1-4684-7035-2
Softcover ISBN
978-1-4684-7037-6
Edition Number
1
Number of Pages
VIII, 173
Number of Illustrations
13 b/w illustrations
Topics