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Environmental Science Research

Genetic Toxicology of Complex Mixtures

Editors: Waters, M.D., Daniel, F.B., Lewtas, J., Moore, M.M., Nesnow, S. (Eds.)

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  • ISBN 978-1-4684-5850-3
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Softcover $109.00
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About this book

Contained in this volume are the proceedings of the international conference on the "Genetic Toxicology of Complex Mixtures," held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the "Fifth International Conference on Environmental Mutagens" and the seventh in a biennial series of conferences on "Short-term Bioassays in the Analysis of Complex Environmental Mixtures. " Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods of genetic toxicology and analytical chemistry in the evaluation of chemical mixtures as they exist in the environment. This conference emphasized the study of genotoxicants in air and water, and the assessment of human exposure and cancer risk. The latest strategies and methodologies for biomonitoring of genotoxicants (including transformation products) were described in the context of the ambient environment. Source character­ ization and source apportionment were discussed as an aid to understand­ ing the origin and relative contribution of various kinds of complex mix­ tures to the ambient environment. Similarly, investigations of genotoxi­ cants found in the indoor environment (sidestream cigarette smoke) and in drinking water (chlorohydroxyfuranones) were given special attention in terms of their potential health impacts. New molecular techniques were described to enable more precise quantitation of internal dose and dose­ to-target tissues. The emphasis of presentations on exposures/effects assessment was on integrated quantitative evaluation of human exposure and potential health effects.

Table of contents (27 chapters)

  • Development and Application of New Methodologies Applicable to Research on Complex Environmental Mixtures

    Lohman, P. H. M. (et al.)

    Pages 1-9

  • Identification of Genotoxic Agents in Complex Mixtures of Air Pollutants

    Schuetzle, Dennis (et al.)

    Pages 11-32

  • Human Exposure to Airborne Mutagens Indoors and Outdoors Using Mutagenesis and Chemical Analysis Methods

    Matsushita, Hidetsuru (et al.)

    Pages 33-56

  • Genetic Toxicology of Airborne Particulate Matter Using Cytogenetic Assays and Microbial Mutagenicity Assays

    Barale, Roberto (et al.)

    Pages 57-71

  • Indoor and Outdoor Sources of Airborne Mutagens in Nonurban Areas

    Houdt, J. J. (et al.)

    Pages 73-87

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-5850-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-5852-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetic Toxicology of Complex Mixtures
Editors
  • Michael D. Waters
  • F.Bernhard Daniel
  • Joellen Lewtas
  • Martha M. Moore
  • Stephen Nesnow
Series Title
Environmental Science Research
Series Volume
39
Copyright
1990
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-5850-3
DOI
10.1007/978-1-4684-5850-3
Softcover ISBN
978-1-4684-5852-7
Edition Number
1
Number of Pages
384
Topics