Nato Science Series A:

Targeting of Drugs With Synthetic Systems

Authors: Gregoriadis, Gregory, Senior, Judith, Poste, George

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eBook 71,39 €
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  • ISBN 978-1-4684-5185-6
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Softcover 90,47 €
price for Spain (gross)
  • ISBN 978-1-4684-5187-0
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About this book

Targeting of drugs via carrier systems to sites in the body in need of pharmacologic intervention is a rapidly growing area of research in the treatment or prevention of disease. It has evolved from the need to preferentially deliver drugs, enzymes, vitamins, hormones, antigens, etc. to target cells and organs so as to avoid toxicity, waste of drugs through premature secretion or inactivation and at the same time render treatment more convenient and cost-effective. A wide assortment of naturally occ­ urring or semi-synthetic drug carriers (e. g. antibodies, glycoproteins, lectins, peptide hormones, cells and liposomes), their inter action with relevant receptors and mediation of optimal pharmacological action were discussed in the two previous NATO Advanced Studies Institutes (ASI) of this series, "Targeting of Drugs" and "Receptor-Mediated Targeting of Drugs", the proceedings of wh ich were published by Plenum in 1982 and 1984 respectively. This book contains the proceedings of the 3rd NATO ASI "Targeting of Drugs with Synthetic Systems" held as be fore at Cape Sounion, Greece during 24 June-5 July 1985. It deals mostly with man-made carriers such as a variety of polymers, matrices, liposomes and other colloidal micro­ particles. The twenty chapters discuss the interaction of such carriers with the biological milieu, approaches to bypass the reticuloendothelial system (or, when needed, take advantage of its interception of carriers to optimally deliver drugs to phagocytes) and ways to improve delivery to specific cells, often with the help of carrier-linked ligands.

Table of contents (20 chapters)

  • Mannose Binding Proteins in the Liver and Blood

    Summerfield, John A.

    Pages 1-12

    Preview Buy Chapter 30,19 €
  • Cell Membrane Molecules on Neoplastic Cells: Their Role in Malignant Cell Transformation and Dissemination

    Olsson, Lennart (et al.)

    Pages 13-23

    Preview Buy Chapter 30,19 €
  • Tumor-Associated Glycolipid Markers: Possible Targets for Drug and Immuno-Toxin Delivery

    Hakomori, Sen-itiroh

    Pages 25-40

    Preview Buy Chapter 30,19 €
  • Interaction of Macromolecular Drugs with Receptors

    Pitha, Josef

    Pages 41-55

    Preview Buy Chapter 30,19 €
  • Endocytosis and Lysosomes: Recent Progress in Intracellular Traffic

    Lloyd, J. B.

    Pages 57-63

    Preview Buy Chapter 30,19 €

Buy this book

eBook 71,39 €
price for Spain (gross)
  • ISBN 978-1-4684-5185-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 90,47 €
price for Spain (gross)
  • ISBN 978-1-4684-5187-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Targeting of Drugs With Synthetic Systems
Authors
Series Title
Nato Science Series A:
Series Volume
113
Copyright
1986
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-5185-6
DOI
10.1007/978-1-4684-5185-6
Softcover ISBN
978-1-4684-5187-0
Edition Number
1
Number of Pages
308
Number of Illustrations and Tables
50 b/w illustrations
Topics