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Reproductive Biology

Immunological Approaches to Contraception and Promotion of Fertility

Editors: Talwar, Gursaran (Ed.)

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About this book

Contraceptive research has entered the new age of vaccines. Realistic prospects exist for the development of an entirely new battery of vaccines for use in human and veterinary medicine. Among them may be anti-fertility vaccines, based on physiological mechanisms applicable to either the female or male. This volume is a comprehensive review - a status report - of the subjects including fundamental work on the search for useful epitopes and ranging to applied vaccinology. One vaccine to prevent pregnancy, for use by women, has already been studied extensively. G.P. Talwar, the volume's editor and his colleagues in New Oelhi, India, published in 1976 a landmark series of papers describing the immunological properties of a preparation consisting of the alum-precipitated beta-subunit of human chorionic gonadotropin (hCG) chemically linked to tetanus toxoid. The principle of enhancing antigenicity of a self-protein by linkage of the epitope to a carrier protein was employed and tested clinically. These trials, carried out under the auspices of the Indian Council for Medical Research, were the first application of the carrier protein concept for a vaccine for human use. The encouraging results stimulated a wave of research not only on the use of hCG-based vaccines, but on other antigens as well.

Table of contents (44 chapters)

  • Inaugural Remarks

    Wallace, Craig K.

    Pages 1-2

  • Inaugural Remarks

    Alexander, Duane

    Pages 3-4

  • Whence the Anti Hormones?

    Hertz, Roy

    Pages 5-15

  • Immunological Approaches to Contraception: The Need, Basic Premise, and Overview

    Talwar, G. P.

    Pages 17-24

  • Lack of Toxicological Effects Following Seven Years of Active Immunization of Rhesus Monkeys with the β-Subunit of Ovine Luteinizing Hormone

    Thau, R. B. (et al.)

    Pages 25-33

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-1-4684-5140-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-1-4684-5142-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Immunological Approaches to Contraception and Promotion of Fertility
Editors
  • Gursaran Talwar
Series Title
Reproductive Biology
Copyright
1986
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-5140-5
DOI
10.1007/978-1-4684-5140-5
Softcover ISBN
978-1-4684-5142-9
Edition Number
1
Number of Pages
X, 442
Number of Illustrations and Tables
68 b/w illustrations
Topics