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Advances in Experimental Medicine and Biology

Host Defenses to Intracellular Pathogens

Proceedings of a conference held in Philadelphia, Pennsylvania, June 10-12, 1981

Editors: Eisenstein, Toby, Actor, Paul, Friedman, Herman (Eds.)

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About this book

The subject matter of this volume was the basis for a confer­ ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro­ organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.

Table of contents (48 chapters)

Table of contents (48 chapters)
  • Introduction and Historical Perspective

    Pages 1-4

    Eisenstein, Toby K.

  • Oxygen Independent Microbicidal Mechanisms of Human Polymorphonuclear Leukocytes

    Pages 5-17

    Spitznagel, John K. (et al.)

  • Oxidative Metabolism of Leukocytes and Its Relationship to Bactericidal Activity

    Pages 19-30

    DeChatelet, Lawrence R. (et al.)

  • Some Paradoxes of Macrophage Function

    Pages 31-50

    Goren, Mayer B.

  • Genetic Disorders of Granulocyte Function: What they Tell Us about Normal Mechanisms

    Pages 51-59

    Root, Richard K.

Buy this book

eBook $129.00
price for USA in USD
  • ISBN 978-1-4684-4481-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4684-4483-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Host Defenses to Intracellular Pathogens
Book Subtitle
Proceedings of a conference held in Philadelphia, Pennsylvania, June 10-12, 1981
Editors
  • Toby Eisenstein
  • Paul Actor
  • Herman Friedman
Series Title
Advances in Experimental Medicine and Biology
Series Volume
162
Copyright
1983
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-4481-0
DOI
10.1007/978-1-4684-4481-0
Softcover ISBN
978-1-4684-4483-4
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XV, 538
Topics

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