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Advances in Experimental Medicine and Biology

Immunobiology of Proteins and Peptides—II

Editors: Atassi, M.Zouhair (Ed.)

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About this book

The immune response is largely dependent on molecular inter­ actions involving proteins. The recognition of antigen molecules, whether they are proteins or non-proteins, whether they are self or non-self, takes place at the molecular-cellular interface through membrane receptor molecules that are proteins. The initial step of recognition activates a complex series of cellular events requiring some mechanism of cell-cell interactions and communi­ cations, eventually leading to antibody production. This biolo­ gical cascade is controlled at several positions along its con­ secutive pathways by protein molecules, either in the free form or as receptors on membranes of cells committed to this activity. Clearly, then, the proper understanding of the response by cells of the immune system will depend, to a great measure, on the definition of the molecular events involving protein interactions. Obviously, cells work via molecules and molecules work via cells and, at this level of functional resolution, molecular immunology and cellular immunology will merge and will depend heavily on protein chemistry.

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Autoimmunity to Myelin Basic Protein

    Pages 3-22

    Swanborg, Robert H. (et al.)

  • The Use of Hybridoma Antibodies to Probe the Antigenic Determinants of Thyroglobulin

    Pages 23-35

    Rose, N. R. (et al.)

  • The Major B and T Cell Determinant on Pigeon Cytochrome c in B10.A Mice

    Pages 37-51

    Hannum, Charles (et al.)

  • Helper T Cells Specific for Protein Antigens: Role of Self Major Histocompatibility Complex and Immunoglobulin Gene Products

    Pages 53-71

    Janeway, Charles A., Jr. (et al.)

  • Dissection of the Molecular Parameters for T-Cell Recognition of a Myoglobin Antigenic Site

    Pages 73-93

    Young, Colin R. (et al.)

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-1-4684-4331-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-1-4684-4333-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Immunobiology of Proteins and Peptides—II
Editors
  • M.Zouhair Atassi
Series Title
Advances in Experimental Medicine and Biology
Series Volume
150
Copyright
1982
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-4331-8
DOI
10.1007/978-1-4684-4331-8
Softcover ISBN
978-1-4684-4333-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 230
Topics