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Basic Life Sciences

Genetic Engineering of Microorganisms for Chemicals

Editors: Hollaender, Alexander (Ed.)

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  • ISBN 978-1-4684-4142-0
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Softcover $149.99
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About this book

The normal course of most biologically catalyzed processes is tightly regulated at the genetic and physiological levels. The regulatory mechanisms are diverse, sometimes redundant, and it is becoming increasingly apparent that, at the genetic level, the range of mechanisms may be limited only by the permutations and combina­ tions available. For each microbial cell, evolution appears to have resulted in maximized advantage to that cell, achieving regulatory balance. Genetic engineering encompasses our attempts to perturb the genetic regulation of a cell so that we may obtain desired other than normal outcomes, such as increased product formation, or new product formation. Following the groundwork established by a preceding symposium (Trends in the Biology of Fermentations for Fuels and Chemicals, Brookhaven National Laboratory, December 1980), the initial planning for this conference envisioned the juxtaposition of molecular genetic expertise and microbial biochemical expertise. The resultant interaction should encourage new and extended ideas for the improve­ ment of strains and for the generation of new regulatory combina­ tions to enhance microbial chemical production from cheap and abundant (including waste) substrates. The interaction should also demonstrate that new discoveries at the basic level remain essential to progress in genetic engineering. New genetic regulatory combina­ tions require new studies of physiology and biochemistry to assure understanding and control of the system. New biochemical reactions necessitate new studies of genetic and regulatory interaction.

Table of contents (33 chapters)

  • Introduction

    Gunsalus, Irwin C.

    Pages 1-2

  • Welcoming Remarks

    Hollaender, Alexander

    Pages 3-4

  • Plasmids as Vectors for Gene Cloning: Past, Present, and Future Use

    Helinski, Donald

    Pages 5-24

  • Strategies: Techniques and Molecular Systems Chairman’s Introduction

    Hotchkiss, Rollin D.

    Pages 25-27

  • Cloning Vectors Derived from Bacterial Plasmids

    Bittner, Michael (et al.)

    Pages 29-49

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4684-4142-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.99
price for USA in USD
  • ISBN 978-1-4684-4144-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetic Engineering of Microorganisms for Chemicals
Editors
  • Alexander Hollaender
Series Title
Basic Life Sciences
Series Volume
19
Copyright
1982
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-4142-0
DOI
10.1007/978-1-4684-4142-0
Softcover ISBN
978-1-4684-4144-4
Edition Number
1
Number of Pages
XIII, 486
Topics