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Opioid Dependence

Mechanisms and Treatment

Authors: Wikler, Abraham

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eBook $84.99
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  • ISBN 978-1-4684-3866-6
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Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-3868-0
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About this book

A major problem in the treatment of opioid dependence has been the persistence of relapse despite detoxification and enforced prolonged abstention from drug use, with or without conventional psychotherapy and other efforts at rehabilitation. Both initial addiction and subsequent relapses are usually ascribed to the quest for opioid-produced euphoria in persons with character disorders. This formulation is in accord with one-half of the common sense "pleasure-pain" principle, but it ignores the other half, namely, the long-lasting dysphoric consequences of re­ peated opioid use (distressing abstinence phenomena, sexual distur­ bances, disruption of marital status, unemployment, enmeshment in criminal activities, arrests, and imprisonment). In any case, the pleasure-pain principle is an empty tautology since it is incapable of refutation by any conceivable objective data that might seem contradic­ tory, inasmuch as it can be "saved" by invocation of untestable uncon­ scious intervening variables. Less tied to the pleasure-pain principle is the view that relapse is due to long-lasting sequelae of previous opioid addiction, resulting from complex conditioning processes, both operant and classical, involving pharmacological, environmental, social and personal variables. In this view, relapse is not simply a re-enactment of initial opioid use, but is a "disease, sui generis" a disease of its own kind. The factors contributing to this disease, sui generis are reviewed in this book.

Table of contents (8 chapters)

  • The Problems of Opioid and Other Drug Dependencies

    Wikler, Abraham, M.D.

    Pages 1-24

  • The Etiology of Opioid Dependence

    Wikler, Abraham, M.D.

    Pages 25-36

  • Opioid Analgesics and Opioid Antagonists

    Wikler, Abraham, M.D.

    Pages 37-67

  • Opioid Receptors and Endogenous Opioid Peptides

    Wikler, Abraham, M.D.

    Pages 69-94

  • Mechanisms of Opioid Analgesia

    Wikler, Abraham, M.D.

    Pages 95-140

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-3866-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-3868-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Opioid Dependence
Book Subtitle
Mechanisms and Treatment
Authors
Copyright
1980
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-3866-6
DOI
10.1007/978-1-4684-3866-6
Softcover ISBN
978-1-4684-3868-0
Edition Number
1
Number of Pages
XIV, 256
Topics