Current Trends in Histocompatibility

Current Trends in Histocompatibility

Volume 2 Biological and Clinical Concepts

Editors: Reisfeld, Ralph (Ed.)

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About this book

Information about histocompatibility antigens is expanding so rapidly that of all advances. In these volumes, we have it is difficult to remain abreast made an effort to bring together the most current work on topics that have generated most of the recent advances and discussions. We have asked each author to present and interpret his most current work, and we have judiciously refrained from imposing our own prejudices and viewpoints. Although there is obvious overlap in some individual topics, we have encouraged this to provide the reader with as many different and some­ times opposing viewpoints as possible. This approach will, we hope, give a broad overview of current ideas in the field. We wish to thank all contributors for their timely and exciting manu­ scripts, and we sincerely hope that the reader will benefit from these volumes. R. A. Reisfeld S. Ferrone La Jolla vii Contents I. Role of Histocompatibility Antigens in Cell-Cell Interaction Chapter 1 Histocompatibility Antigens and the T-Cell Repertoire . . . . . . . . . . . . . . 3 Harald von Boehmer 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. H-2 Restriction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. H-2 Restriction of T Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 2. B Cells Are Not H-2-Restricted . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3. H-2-Linked Ir Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3. 1. Influence on the T-Cell Repertoire . . . . . . . . . . . . . . . . . . . . . . . . 5 3. 2. H-2-Gene Complementation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3. 3. The B-Cell Repertoire Is Not Directly Influenced by H-2-Linked Ir Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Frequency of Cells Specific for Allogeneic H-2 Antigens . . . . . . . . 12 4. 1. Allospecific T Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. 2. Allospecific B Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Histocompatibility Antigens and the T-Cell Repertoire

    Pages 3-18

    Boehmer, Harald

  • Continuously Proliferating Allospecific T-Cell Lines

    Pages 19-34

    Dennert, Gunther

  • The Dual Specificity of Virus-Immune T Cells

    Pages 35-57

    Doherty, Peter C. (et al.)

  • Hapten Recognition by Cytotoxic T Cells

    Pages 59-80

    Henney, Christopher S. (et al.)

  • New Thoughts on the Control of Self-Recognition, Cell Interactions, and Immune Responsiveness by Major Histocompatibility Complex Genes

    Pages 81-103

    Katz, David H.

Buy this book

eBook $99.00
price for USA in USD
  • ISBN 978-1-4684-3761-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-1-4684-3763-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Current Trends in Histocompatibility
Book Subtitle
Volume 2 Biological and Clinical Concepts
Editors
  • Ralph Reisfeld
Copyright
1981
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-3761-4
DOI
10.1007/978-1-4684-3761-4
Softcover ISBN
978-1-4684-3763-8
Edition Number
1
Number of Pages
XVI, 311
Topics