Calcium in Drug Action

Editors: Weiss, G. B. (Ed.)

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About this book

Anyone surveying physiological and pharmacological journals can readily see that the biological actions of calcium ion are of increasingly widespread current interest. The scope of investi­ gated actions and reactions in which a role for calcium ion is of some importance is so numerous as to convey the impression that calcium ion is everywhere and interacts with everything. This being so, the challenge in contemporary research is to focus on investigation of those actions of calcium ion which, in some manner, influence either significant physiological parameters or the manner in which pharmacological agents act. This multi-authored book originated from a more limited Symposium on "Importance of Calcium as a Primary Locus of Drug Action" co-chaired by myself and Dr. Frank R. Goodman at the April, 1977 FASEB meeting in Chicago. This Symposium was organized in response to a perceived need for increased communication among 2 workers in different areas of Ca +-related research. In the pro­ cess of selecting the maximum of six areas for presentation within the format provided, it soon became apparent that this would result in only a limited sampling of current research efforts. Expansion of the number of areas to fourteen within a book format appeared to be the most logical mechanism to provide a more coherent inter­ disciplinary approach to consideration of various aspects of the 2 roles of Ca + in drug action. This is not to imply that all rele­ 2 vant Ca +-related areas are surveyed within this volume.

Table of contents (14 chapters)

  • Calcium, Calcium Translocation, and Specific Calcium Antagonists

    Rosenberger, L. (et al.)

    Pages 3-31

  • Surface Calcium in the Heart: Its Function and Role in Drug Action

    Frank, Joy S.

    Pages 33-56

  • Quantitative Measurement of Binding Sites and Washout Components for Calcium Ion in Vascular Smooth Muscle

    Weiss, George B.

    Pages 57-74

  • Calcium in Smooth Muscle Function

    Hurwitz, Leon (et al.)

    Pages 75-93

  • Effects of Calcium on Adenylate Cyclase, as Part of the Ca2+-cAMP Feedback in Biological Communication

    Rodan, Gideon A.

    Pages 97-133

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-3354-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-3356-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Calcium in Drug Action
Editors
  • G. B. Weiss
Copyright
1978
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-3354-8
DOI
10.1007/978-1-4684-3354-8
Softcover ISBN
978-1-4684-3356-2
Edition Number
1
Number of Pages
X, 366
Topics