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Advances in Experimental Medicine and Biology

Membrane Toxicity

Editors: Miller, M. W. (Ed.)

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About this book

Research on the study of membrane toxicity has advanced a great deal in a relatively short period of time, prompting scientists to re-examine the problems associated with carriers, receptors and reactors to toxic substances. This book presents current research on the responses of membranes to toxic sub­ stances both by direct observation of macromolecules reacting with these substances and by inference from data on the bio­ chemical responses of cells and cell fractions. Two basic areas of membrane toxicity are analyzed by a large number and variety of scientists in this field. The first area is the effect of various toxic substances on membrane structure and function. The second area is where the membrane serves as the site of rate limiting step of the transport of various toxic substances. The aim of the book is to evaluate present concepts of membrane structure and function in relation to exposure to envir­ onmental toxicants. The book is divided into five sessions: 1. Xenobiotics and Membrane Transport 2. Cellular Responses to Toxins 3. Effects of Membranes and Receptors 4. Modification of Membrane Function by Toxicological Agents 5. Toxic Chemicals as Molecular Probes of Membrane Structure and Function Each paper is generally concluded by an edited discussion which contains many useful and interesting additional insights in each subject area. v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this conference by the U. S. Energy Research and Development Administration, the Environmental Protection Agency and the University of Rochester.

Table of contents (23 chapters)

Table of contents (23 chapters)
  • Effect of P-Chloromercuribenzoate (pCMB), Ouabain and 4-Acetamido-4′ISO-Thiocyamatostilbene-2,2′-Disulfonic Acid (Sits) on Proximal Tubular Transport Processes

    Pages 3-13

    Ullrich, K. J. (et al.)

  • Heavy Metals and Membrane Functions of an Alveolar Epithelium

    Pages 15-39

    Gatzy, John T.

  • The Localization of Ion-Selective Pumps and Paths in the Plasma Membranes of Turtle Bladders

    Pages 41-66

    Brodsky, William A. (et al.)

  • Membrane Water Channels and SH-Groups

    Pages 67-83

    Sha’afi, R. I. (et al.)

  • Membrane Transport of Antifolates as a Critical Determinant of Drug Cytotoxicity

    Pages 85-113

    Goldman, I. David

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-1-4684-3279-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-1-4684-3281-7
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Membrane Toxicity
Editors
  • M. W. Miller
Series Title
Advances in Experimental Medicine and Biology
Series Volume
84
Copyright
1977
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-3279-4
DOI
10.1007/978-1-4684-3279-4
Softcover ISBN
978-1-4684-3281-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 553
Topics

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