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Advances in Experimental Medicine and Biology

Immunologic Phylogeny

Editors: Hildemann, W. (Ed.)

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About this book

There are two now classic reasons for the widespread and con­ tinuing interest in the phylogeny of immune reactivities and structure. First is the fundamental concern of biologists with the evolution of defense mechanisms. We are eager to discover origins, mechanisms, and adaptive specializations of immunocompetence because the very existence of individuals and entire species is involved in a most essential way. Second is the strong biomedical interest in adaptive immune mechanisms to increase understanding of health and disease in man. If man and placental mammals represent the quin­ tessence of immunoresponsiveness with complex interdependent path­ ways, the less elaborate but fully functional systems of immunity in "lower" animals proffer insights applicable to immediate con­ cerns in medicine. Recent approaches to organ transplantation, immunotherapy of cancer and repair of immunodeficiency diseases, to name just a few areas, have depended greatly on phylogenetic per­ spectives. In a larger sense, intelligent wildlife conservation, utilization of food resources, and adequate environmental protection all hinge on knowing how diverse species survive or otherwise suc­ cumb to insults, injuries, and disease. The phylogenetic immunologist also seeks detailed information on the structure of the immunoglobulins which relates directly to the evolutionary history of living animals. Perhaps genetic mech­ anisms responsible for the evolution of these proteins may be re­ vealed as spin-off information. The vast number of immunoglobulin specificities and effector structures, coupled with the remarkable phylogenetic conservation of certain polypeptide regions, makes these molecules especially useful to protein chemists as well as immunologists.

Table of contents (47 chapters)

Table of contents (47 chapters)
  • Tridacnin, a Potent Anti-Galactan Precipitin from the Hemolymph of Tridacna Maxima (Röding)

    Pages 3-11

    Baldo, B. A. (et al.)

  • Anti-Galactan Precipitins in the Hemolymph of Tridacna Maxima and Limulus Polyphemus

    Pages 13-18

    Cohen, E. (et al.)

  • Protectins in Argentine Mollusks: Immunological and Immunochemical Aspects

    Pages 19-28

    Palatnik, M. (et al.)

  • Immunologic Significance of Specificities of Cellular Agglutinins of Limulus Polyphemus

    Pages 29-31

    Cohen, Elias

  • Some Specific Aspects of Cell-Surface Recognition by Sipunculid Coelomocytes

    Pages 35-44

    Cushing, John E. (et al.)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-1-4684-3261-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Immunologic Phylogeny
Editors
  • W. Hildemann
Series Title
Advances in Experimental Medicine and Biology
Series Volume
64
Copyright
1975
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-3261-9
DOI
10.1007/978-1-4684-3261-9
Softcover ISBN
978-1-4684-3263-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 485
Number of Illustrations
83 b/w illustrations
Topics

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