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Aging in Cell and Tissue Culture

Proceedings of a symposium on “Aging in Cell and Tissue Culture” held at the annual meeting of the European Tissue Culture Society at the Castle of Žinkovy in Czechoslovakia, May 7–10, 1969

Authors: Holeckova, E.

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About this book

The annual meeting of the European Tissue Culture ., Society was held at the Castle of Zinkovy in Czechoslovakia from May 7-10,1969. Included as part of this meeting was a symposium on "Aging in Cell and Tissue Culture." This volume contains the papers presented at that symposium. The use of cell and tissue culture techniques to study the mechanism of aging is not new. For example, it has long been known that age-associated changes which occur in plasma can inhibit cell proliferation in vitro; also that the time lapse prior to cell migration from ex­ planted tissue fragments increases with increasing age. These are both examples of the expression in vitro of aging in vivo. More recently, attention has been focused on the occurrence of senescence in vitro. These investi­ gations have included studies of alterations in non­ dividing cell cultures, and to a somewhat greater extent, of age-related changes in the proliferative capacity of cells in vitro. For example, cells derived from human fetal lung retain many properties of normal cells including a stable normal diploid karyotype and these cultures have been shown to have a limited life-span in vitro. In addi­ tion, cultures derived from human adult lung show the same normal characteristics and appear to have a shorter life­ span than cells derived from fetal lung.

Table of contents (9 chapters)

Table of contents (9 chapters)
  • Opening Remarks

    Pages 1-6

    Holečková, Emma (et al.)

  • Cell Strain Senescence in Vitro: Cell Culture Anomaly or an Expression of a Fundamental Inability of Normal Cells to Survive and Proliferate

    Pages 7-24

    Hay, Robert J.

  • A Theoretical and Experimental Approach to the Relationship Between Cell Variability and Aging in Vitro

    Pages 25-39

    Simons, J. W. I. M.

  • Changes of the Latent Period of Explanted Tissues During Ontogenesis

    Pages 41-56

    Soukupová, Milena (et al.)

  • Lipid Metabolism in Human Diploid Cells

    Pages 57-82

    Kritchevsky, David (et al.)

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-1821-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4684-1823-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Aging in Cell and Tissue Culture
Book Subtitle
Proceedings of a symposium on “Aging in Cell and Tissue Culture” held at the annual meeting of the European Tissue Culture Society at the Castle of Žinkovy in Czechoslovakia, May 7–10, 1969
Authors
Copyright
1970
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-1821-7
DOI
10.1007/978-1-4684-1821-7
Softcover ISBN
978-1-4684-1823-1
Edition Number
1
Number of Pages
XX, 164
Topics