Normal Renal Function

1. Front Matter

   Pages i-viii

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2. Introduction

   1. Introduction

      • W. J. O’Connor

      Pages 1-10

3. Acute Experiments on Normal Renal Function

   1. Front Matter

      Pages 11-11

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   2. Glomerular Filtration Rate

      • W. J. O’Connor

      Pages 13-45

   3. Renal Nerves as an Agent Acting on the Kidneys

      • W. J. O’Connor

      Pages 47-53

   4. Excretion of Urea

      • W. J. O’Connor

      Pages 55-75

   5. Excretion of Sulphate

      • W. J. O’Connor

      Pages 77-85

   6. Excretion of Phosphate

      • W. J. O’Connor

      Pages 87-96

   7. Excretion of Potassium

      • W. J. O’Connor

      Pages 97-110

   8. Excretion of Sodium

      • W. J. O’Connor

      Pages 111-144

   9. Excretion of Chloride and Bicarbonate; Ammonium in Urine

      • W. J. O’Connor

      Pages 145-161

   10. The Antidiuretic Action of Vasopressin

       • W. J. O’Connor

       Pages 163-178

   11. Release of Antidiuretic Hormone from the Neurohypophysis

       • W. J. O’Connor

       Pages 179-207

   12. Acute Experiments on the Volume of the Urine

       • W. J. O’Connor

       Pages 209-228

   13. Acute Experiments on Drinking by Dogs

       • W. J. O’Connor

       Pages 229-246

4. Balance Experiments

   1. Front Matter

      Pages 247-247

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   2. Intake of Amino-N and Excretion of Urea

      • W. J. O’Connor

      Pages 249-264

   3. Intake of Sulphur and Excretion of Sulphate

      • W. J. O’Connor

      Pages 265-272

   4. Intake of Phosphorus and Excretion of Phosphate

      • W. J. O’Connor

      Pages 273-281

   5. Intake and Excretion of Potassium

      • W. J. O’Connor

      Pages 283-297

This book has developed from an earlier monograph, 'Renal Function' (1962; London, Edward Arnold). It retains the general purpose of that book in relating the composition of the blood to the volume and com­ position of the urine of animals, including the new data of the intervening 20 years. As indicated by its title, this new book also has the particular purpose of studying the urine of animals in a normal environment and eating food usual to the species. Renal physiology illustrates a dilemma which arises also in other fields. Advanced technology, harnessed by accumulated experimental skill, now allows detailed investigation of basal processes. Micropuncture experiments have greatly advanced our understanding of the processes of glomerular fil­ tration and tubular reabsorption and have contribut­ ed to the wider discussion of the physicochemical nature of the movement of water and ions across cell surfaces. But experiments at microscopic or cell­ ular level demand experimental conditions in which the systems are abstracted from their natural en­ vironment, either as isolated perfused preparations or with the anaesthetised animal merely providing support for a tissue left in situ. The arguments from such experiments, important though they are towards understanding the basal processes, readily become remote from the reality of the normal animal.

• absorption
• blood
• cell
• physiology
• tissue
• water

• University of Leeds, UK

  W. J. O’Connor

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