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Signal Transduction by G Protein-Coupled Receptors

Bioenergetics and G Protein Activation: Proton Transfer and GTP Synthesis to Explain the Experimental Findings

  • Book
  • © 1997

Overview

Authors:
  1. Paul H. J. Nederkoorn

    1. Leiden/Amsterdam Center for Drug Research, Amsterdam, The Netherlands

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  2. Henk Timmerman

    1. Leiden/Amsterdam Center for Drug Research, Amsterdam, The Netherlands

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  3. Gabriëlle M. Donné-Op Kelder

    1. Leiden/Amsterdam Center for Drug Research, Amsterdam, The Netherlands

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Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Bioenergetical Mechanisms, Hydrogen-Bonded Chains and Proton Transfer Mechanisms

    1. Front Matter

      Pages 1-1
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    2. Bioenergetics

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 3-16

    3. Primary and Secondary Proton Pumps

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 17-26

    4. ATP Hydrolysis and Synthesis Mechanisms

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 27-39

  3. Proton-Transferring Hydrogen-Bonded Chains and the Ternary Complex: The Ternary Complex as a GTP Synthase

    1. Front Matter

      Pages 41-41
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    2. G Protein-Coupled Receptors and G Proteins

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 43-62

    3. The (Extended) Ternary Complex Model ([E]TCM) for G Protein Activation

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 63-73

    4. Nucleotide Exchange Reactions and G Protein Activation

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 75-92

    5. A New Mechanism for G Protein Activation

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 93-111

    6. Principles of a New Molecular Mechanism for Signal Transduction

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 113-141

    7. Conclusions and Future Perspectives

      • Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op den Kelder
      Pages 143-148

  4. Back Matter

    Pages 149-151
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Keywords

Authors and Affiliations

  • Leiden/Amsterdam Center for Drug Research, Amsterdam, The Netherlands

    Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op Kelder

Bibliographic Information

  • Book Title: Signal Transduction by G Protein-Coupled Receptors

  • Book Subtitle: Bioenergetics and G Protein Activation: Proton Transfer and GTP Synthesis to Explain the Experimental Findings

  • Authors: Paul H. J. Nederkoorn, Henk Timmerman, Gabriëlle M. Donné-Op Kelder

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-1-4684-1407-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Softcover ISBN: 978-1-4684-1409-7Published: 16 April 2013

  • eBook ISBN: 978-1-4684-1407-3Published: 29 June 2013

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: XIV, 151

  • Number of Illustrations: 11 b/w illustrations, 2 illustrations in colour

  • Topics: Medical Microbiology

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